[Changes in lipid metabolism and renewal of sialic acids in the composition of glycoproteins of adipose tissue during carbohydrate loading].

With an increase in content of sugar in a diet from 10% to 50% of the caloric value the rate of synthesis and accumulation of lipids were increased in perinephric adipose tissue of rats exhibiting the maximal values at 30% content of sugar in rations. Under these conditions content of insulin was decreased in blood and half-life of sialic acids was decreased in glycoproteins of adipose tissue. Interrelationship between sensitivity of the adipose tissue receptors to insulin and the half-life of sialic acids was considered. Metabolism of sialic acids was considered. Metabolism of sialic acids appears to be of importance for accumulation of lipids in adipose tissue under conditions of sugar loading.