We present a case of a deep full thickness burn from topical formic acid. Our patient developed a burn over her proximal interphalangeal joint (PIPJ) of her finger, secondary to inappropriate application of an anti-wart treatment. The burn required extensive deridement, and the resultant defect was reconstructed using a subcutaneous flap from the adjacent finger (a reverse cross finger flap). She was reviewed six months post-surgery, and overall she has a sub-optimal result. This incident was referred to the Irish Medicine's Board who have since reviewed the case and ordered the manufacturer to alter their usage instructions.

Download full-text PDF

Source

Publication Analysis

Top Keywords

deep full
8
full thickness
8
thickness burn
8
burn
4
finger
4
burn finger
4
finger topical
4
topical wart
4
wart treatment
4
treatment case
4

Similar Publications

While radiation hazards induced by cone-beam computed tomography (CBCT) in image-guided radiotherapy (IGRT) can be reduced by sparse-view sampling, the image quality is inevitably degraded. We propose a deep learning-based multi-view projection synthesis (DLMPS) approach to improve the quality of sparse-view low-dose CBCT images. In the proposed DLMPS approach, linear interpolation was first applied to sparse-view projections and the projections were rearranged into sinograms; these sinograms were processed with a sinogram restoration model and then rearranged back into projections.

View Article and Find Full Text PDF

Background: Deepening of the nasolabial fold (NLF), drooping of the nasal tip, and facial expressions perceived as angry face, are common esthetic concerns. However, no studies have correlated this set of signs and symptoms with common anatomical causes. We review anatomical considerations of the region and propose a combined treatment modality.

View Article and Find Full Text PDF

Previous estimates of deep soil inorganic nitrogen (N) reservoirs have been mainly limited to desert soils, however, recent evidence suggests that deep soil pools are far more ubiquitous across biomes and therefore may be important for global N budgets. Here, we used observations from 280 deep soil profiles (2-205 m) across a wide array of ecosystem and land cover types to seek insight into the full geospatial variation of deep soil nitrate. Using a random forest machine learning approach we estimate a total deep soil nitrate pool of 15.

View Article and Find Full Text PDF

Flexible Tail of Antimicrobial Peptide PGLa Facilitates Water Pore Formation in Membranes.

J Phys Chem B

January 2025

Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, State Key Laboratory of Medicinal Chemical, Biology College of Chemistry, Nankai University, Tianjin 300071, China.

PGLa, an antimicrobial peptide (AMP), primarily exerts its antibacterial effects by disrupting bacterial cell membrane integrity. Previous theoretical studies mainly focused on the binding mechanism of PGLa with membranes, while the mechanism of water pore formation induced by PGLa peptides, especially the role of structural flexibility in the process, remains unclear. In this study, using all-atom simulations, we investigated the entire process of membrane deformation caused by the interaction of PGLa with an anionic cell membrane composed of dimyristoylphosphatidylcholine (DMPC) and dimyristoylphosphatidylglycerol (DMPG).

View Article and Find Full Text PDF

Background And Aims: The lack of therapeutic response characterizes treatment-resistant depression despite undergoing at least two adequate monotherapy trials with medications from distinct pharmacologic classes. The inability to attain remission in patients diagnosed with major depressive disorder (MDD) is a significant issue of concern within public health. Therefore, the management of treatment-resistant depression (TRD) poses significant obstacles for both patients and healthcare professionals.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!