Aim: of the study was to assess the relationship between advanced glycation end-products measured by skin autofluorescence (AGEs) and pulse wave velocity (PWV) in non-diabetic patients with cardiovascular disease (CVD).
Material And Methods: Skin autofluorescence (AGE--reader, DiagnOptic) and PWV in humero-malleolar segment (PWVhm) were measured in 93 non-diabetic CVD patients (mean age 63.5 years): 28 with ischemic heart disease (IHD) and 65 without IHD from the group with moderate/high risk of development of cardiovascular complications.
Results: Significant positive association was observed between AGEs and PWVhm (r = 0.31, p = 0.003). This correlation was found only in patients without IHD (r = 0.44, p < 0.0003). Positive association AGEs with of age (r = 0.52, p = 0.006) was observed irrespective of IHD. AGEs was not the significant determinant of PWVhm in multiple regression analysis.
Conclusion: Relationship between AGEs and PWVhm was found in non-diabetic moderate/high-risk patients. In contrast to age and systolic blood pressure AGEs was not the significant determinant of PWVhm.
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http://dx.doi.org/10.18565/cardio.2015.6.63-67 | DOI Listing |
Am J Kidney Dis
January 2025
Department of Epidemiology and Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. Electronic address:
Rationale & Objective: Arterial stiffness is associated with prevalent chronic kidney disease (CKD). Whether arterial stiffness is prospectively associated with incident CKD is inconclusive.
Study Design: Longitudinal cohort study.
Int J Biol Macromol
January 2025
School of Textile Science and Engineering, Tiangong University, Tianjin 300387, China.
The importance of continuous and reliable pulse wave monitoring is constantly being increased in health signal monitoring and disease diagnoses. Flexible pressure sensors with high sensitivity, low hysteresis and fast response time are an effective means for monitoring pulses. Herein, a special wave-shaped layered porous structure of carbonized wood cellulose sponge (CWCS) was constructed based on natural wood (NW).
View Article and Find Full Text PDFJ Cereb Blood Flow Metab
January 2025
Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Pontypridd, UK.
To what extent sildenafil, a selective inhibitor of the type-5 phosphodiesterase modulates systemic redox status and cerebrovascular function during acute exposure to hypoxia remains unknown. To address this, 12 healthy males (aged 24 ± 3 y) participated in a randomized, placebo-controlled crossover study involving exposure to both normoxia and acute (60 min) hypoxia (Fi = 0.14), followed by oral administration of 50 mg sildenafil and placebo (double-blinded).
View Article and Find Full Text PDFSensors (Basel)
January 2025
Department of Psychological and Cognitive Sciences, Tsinghua University, Beijing 100084, China.
The objective identification of depression using physiological data has emerged as a significant research focus within the field of psychiatry. The advancement of wearable physiological measurement devices has opened new avenues for the identification of individuals with depression in everyday-life contexts. Compared to other objective measurement methods, wearables offer the potential for continuous, unobtrusive monitoring, which can capture subtle physiological changes indicative of depressive states.
View Article and Find Full Text PDFSensors (Basel)
January 2025
Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, 168 Litang Road, Changping District, Beijing 102218, China.
(1) Background: To develop a novel capillary refill time measurement system and evaluate its reliability and reproducibility. (2) Methods: Firstly, the utilization of electromagnetic pressure technology facilitates the automatic compression and instantaneous release of the finger. Secondly, the employment of pressure sensing technology and photoelectric volumetric pulse wave analysis technology enables the dynamic monitoring of blood flow in distal tissues.
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