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A rare case of adult-onset vanishing white matter leukoencephalopathy with movement disorder, expressing homozygous EIF2B3 and PRKN pathogenic variants.
BMC Neurol
January 2025
Faculty of Medicine, Department of Neurology, Al-Quds University, Jerusalem, Palestine.
Background: Vanishing white matter disease (VWMD) is a rare autosomal recessive leukoencephalopathy. It is typified by a gradual loss of white matter in the brain and spinal cord, which results in impairments in vision and hearing, cerebellar ataxia, muscular weakness, stiffness, seizures, and dysarthria cogitative decline. Many reports involve minors.
View Article and Find Full Text PDFGiant prolactinoma with progressive cranial settling and central herniation: a case report.
J Med Case Rep
December 2024
Department of Neurosurgery, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Background: Giant prolactinoma (size > 4 cm) is a rare condition and accounts for less than 1% of pituitary adenomas. In even rarer cases, these lesions may involve craniocervical structures requiring surgical intervention. The present case is the largest reported giant prolactinoma (99 × 72 × 57 mm).
View Article and Find Full Text PDFHeart in the Brain.
J Assoc Physicians India
December 2024
Neurologist, Department of Neurology, Brain and Spine Centre, Vaikom, Kerala, India.
A 52-year-old man with a 5-year history of diabetes mellitus and chronic renal disease presented with sudden onset left upper limb weakness and numbness at 5 pm, which progressed to quadriplegia by the next day at 2:30 am. He had dysarthria at admission. There were no sensory symptoms in the lower limbs.
View Article and Find Full Text PDFHolocord intramedullary pilocytic astrocytoma mimicking holocord spinal abscess: a case report and literature review.
Childs Nerv Syst
December 2024
Department of Neurosurgery, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Purpose: This report aims to present a case of a child with holocord pilocytic astrocytoma and review the existing literature to provide insights into current management strategies.
Case Presentation: An 11-month-old patient presented with progressive quadriplegia and was initially diagnosed with a spinal abscess. MRI revealed a heterogeneously enhancing cystic intramedullary lesion extending from the cervicomedullary region to the conus medullaris.
A rare case of guidewire migration to central nervous system. A surgical case report.
Int J Surg Case Rep
November 2024
Eric Williams Medical Sciences Complex, Mount Hope, Trinidad and Tobago.
Introduction And Importance: Guidewire localization in breast conserving procedures is commonly performed. Although it is a relatively safe procedure, there are atypical complications that may occur. Here, we highlight a rare case of guidewire migration, affecting both the brain and spine.
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