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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770908PMC
http://dx.doi.org/10.1053/j.gastro.2015.10.022DOI Listing

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Fever for days: A challenging case of dalbavancin-induced fever.

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December 2024

Division of Infectious Diseases, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA.

Dalbavancin is a novel long acting lipoglycopeptide antibiotic with a favorable safety profile approved for treating Acute Bacterial Skin and Skin Structure Infections (ABSSSI) caused by Gram-positive organisms. Given its long half-life, a two-dose regimen can provide effective systemic therapy for up to six weeks, making it an appealing option to avoid prolonged intravenous antibiotic therapy. Herein, we report a case of a 27-year-old male who developed dalbavancin-induced fever while treating Methicillin-sensitive (MSSA) bacteremia.

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Fever has long been recognized as one of the earliest clinical indicators of illness and remains a leading reason for seeking medical care worldwide. It is typically classified based on its duration and underlying etiology. In clinical settings, intractable fever is as common as acute fever, particularly in patients with brain injuries.

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