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Phenol and its chlorinated derivatives are introduced into the environment with wastewater effluents from various industries, becoming toxic pollutants. Phenol-degrading bacteria are important objects of research; among them, representatives of the genus are often highlighted as promising. Strain 7Ba was isolated by enrichment culture.

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  • KB1 is a petroleum-degrading bacterium from the Actinomycetota phylum that utilizes resuscitation-promoting factors (Rpf) to revive dormant cells and support growth.
  • The study specifically investigates the Rpf2 protein in KB1, which has a complex structure with various domains, including DUF348, and examines how deletions of these domains affect its enzymatic and biological activities.
  • Results indicate that removing DUF348 domains significantly reduces both enzyme activity and growth-promoting effects, while also affecting thermal stability, highlighting the importance of these domains in Rpf2's function.
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  • - Antibiotic resistance in bacteria like
  • Streptococcus agalactiae
  • is escalating globally, making it a major health concern, particularly for infants exposed during pregnancy, as these bacteria show resistance to known antibiotics.
  • - There is currently no commercial vaccine for
  • S. agalactiae
  • , but developing one, particularly aimed at protecting newborns through vaccination of pregnant women, has been highlighted as a crucial need by the World Health Organization.
  • - This study utilized immunoinformatics to create a potential mRNA vaccine targeting
  • S. agalactiae
  • , predicting immune responses and demonstrating increased levels of key immune components in an in vivo model after vaccination, indicating promising efficacy.
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  • * The addition of ADS significantly boosted the rate of dechlorination for Aroclor 1260, particularly increasing the removal of meta- and para-chlorine while not altering the dechlorination pathways.
  • * The research also found that ADS led to an increased abundance of important dechlorinating bacteria and associated functional genes, suggesting its potential in isolating and enriching organohalide-respiring bacteria (OHRB) through supplemental techniques.
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Background: Dormancy survival regulator (DosR) and resuscitation-promoting factor (Rpf) antigens of Mycobacterium tuberculosis are activated during dormant phase of tuberculosis (TB). This study evaluates the differential immunogenicity potentials of DosR and Rpf antigens in individuals with latent tuberculosis infection (LTBI) and active TB patients.

Methods: After a literature search in electronic databases, studies were selected by following precise eligibility criteria.

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