Background: Spondylodiscitis refers to an infection of one or more intervertebral disks and vertebrae, most commonly caused by tuberculosis. Initial therapy for spondylodiscitis is drug treatment. Indications for surgical treatment include compression of neural elements, spinal instability or severe deformities. When surgery is indicated, an open technique is still the standard, although video-assisted thoracoscopic surgery (VATS) is described in cases of thoracic disk herniation, scoliosis and tubercular spondylitis.
Case Report: We report a case of a 79-year-old man with progressive back pain, paraparesis and paresthesias in both legs. During assessment, spondylodiscitis with spinal cord compression was diagnosed. Immediate surgical decompression took place by means of VATS. Culture of the tissue obtained revealed Proteus mirabilis. Blood and urine cultures also revealed Proteus mirabilis, a rare cause of spondylodiscitis with an occurrence rate of 0.9%.
Conclusion: VATS offered a minimally invasive access to obtain the diagnosis of pyogenic spondylodiscitis following urosepsis with Proteus mirabilis. Moreover, it provided treatment with abscess drainage and decompression of the spinal cord.
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http://dx.doi.org/10.14444/2055 | DOI Listing |
Pathogens
January 2025
Department of Human Pathology, University of Messina, 98125 Messina, Italy.
The aim of this study was to investigate the differences between nosocomial and community microorganisms isolated from patients with UTI by determining their bacterial profile, antibiotic resistance and ability to produce biofilms. A retrospective study, based on bacterial isolates from consecutive urine samples collected between January 2019 and December 2023, was conducted at a university hospital. The main pathogens isolated from both community and hospital samples were the same, but their frequency of isolation differed.
View Article and Find Full Text PDFAntibiotics (Basel)
January 2025
Department of Dermatovenerology, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
: Chronic wounds, including hidradenitis suppurativa (HS) and venous ulcers (VU), are commonly associated with complex microbial communities that may influence wound healing and treatment outcomes. Understanding microbial diversity and antibiotic resistance patterns is essential in order to optimize therapeutic strategies. This study aimed to investigate the microbial populations and antibiotic resistance profiles in HS and VU patients, comparing the prevalence of common pathogens and their antimicrobial resistance profiles.
View Article and Find Full Text PDFBr Poult Sci
January 2025
State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.
1. This study investigated antimicrobial resistance, virulence factors and genotypic profiling among isolated from three sources (poultry farms, slaughterhouses and retail markets) in the poultry production chain in Zhejiang Province, China, to assess its potential risk to public health.2.
View Article and Find Full Text PDFFront Microbiol
January 2025
Yunnan Joint International R&D Center of Veterinary Public Health, College of Veterinary Medicine, Yunnan Agricultural University, Kunming, China.
Background: is a conditionally pathogenic bacterium that is inherently resistant to polymyxin and tigecycline, largely due to antibiotic resistance genes (ARGs). These ARGs can be horizontally transferred to other bacteria, raising concerns about the Inc plasmid-mediated ARG transmission from , which poses a serious public health threat. This study aims to investigate the presence of Inc plasmid types in pig-derived in Kunming, Yunnan, China.
View Article and Find Full Text PDFCurr Microbiol
January 2025
Fisheries and Marine Resources Technology Discipline, Khulna University, Khulna, 9208, Bangladesh.
Infections caused by antibiotic-resistant bacteria (ARB) result in an estimated 1.27 million human deaths annually worldwide. Surface waters are impacted by anthropogenic factors, which contribute to the emergence and spread of ARB in the aquatic environment.
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