Background: GISTs are mesenchymal tumors representing approximately 1% of all gastrointestinal neoplasia. Their concurrence with colorectal cancers is rare.

Case Report: We present a case of coexistence of colon adenocarcinoma and GIST of the ileum in a 68-year-old white woman.

Conclusions: The coexistence of mesenchymal and epithelial neoplasia is very challenging; further research is needed to clarify the role of oncogenic mutations and signalling pathways in carcinogenesis of neoplasia of various histiogenic origins.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671400PMC
http://dx.doi.org/10.12659/ajcr.894845DOI Listing

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