The gene functions in oogenesis were studied. It was demonstrated that the suppression of expression by RNA interference in follicle cells led to oocyte polarization defects, anomalous cytokinesis in the chorion cells, and aberrant chromatin condensation in follicle cells. No oogenesis abnormalities were observed in females with decreased gene expression in ovarian germline cells. However, embryos produced by such females had a decreased survival rate caused by two peaks of embryonic death.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6027749 | PMC |
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