The present study describes a Japanese patient with pure agraphia displaying differential disturbances in processing Kanji (morphogram) and Kana (syllabogram) letters after an infarction in the middle and superior portions of the left precentral gyrus. Kana errors reflected the patient's difficulty with retrieving both motor and visual letter images, whereas Kanji errors included partial letter stroke omissions or additions. This present case suggests that differences in writing disturbances between Kana and Kanji letters are caused by a differential dependency on letter motor images.
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http://dx.doi.org/10.1016/j.jocn.2015.08.030 | DOI Listing |
Child Care Health Dev
January 2025
Department of Special Education, University of Jeddah, Jeddah, Saudi Arabia.
Background: Learning disabilities, categorized as neurodevelopmental disorders, profoundly impact the cognitive development of young children. These disabilities affect text comprehension, reading, writing and problem-solving abilities. Specific learning disabilities (SLDs), most notably dyslexia and dysgraphia, can significantly hinder students' academic achievement.
View Article and Find Full Text PDFNeurology
January 2025
Sant Pau Memory Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Biomedical Research Institute Sant Pau (IIB Sant Pau), Universitat Autònoma de Barcelona.
Objectives: Atypical variants are rare in genetically determined Alzheimer disease (AD). This case describes a patient with Down syndrome-associated Alzheimer disease (DSAD) who presented with symptoms of posterior cortical atrophy (PCA).
Methods: We conducted a clinical and cognitive evaluation, genotyping, determination of AD biomarkers in CSF, structural MRI, [18F]FDG-PET, and tau-PET ([18F]PI2620) scans.
Neurocase
December 2024
Department of Neurology, Yale School of Medicine, New Haven, CT, USA.
This case report presents the story of Mr. S, a professional orchestral musician with declining musical sight-reading ability, followed by progressive visuospatial and language deficits. Our novel musical assessment battery revealed deficits in music-reading (musical alexia) and music-writing (musical agraphia), with spared auditory perception and expression.
View Article and Find Full Text PDFJ Neuroophthalmol
November 2024
Kellogg Eye Center and Department of Ophthalmology and Visual Sciences (JNS, JDT, SK), University of Michigan, Ann Arbor, Michigan; Departments of Radiology (AS) and Neurology (JDT, SK), University of Michigan, Ann Arbor, Michigan; and Department of Ophthalmology (RDW), Medical College of Wisconsin, Milwaukee, Wisconsin.
Background: Alexia without agraphia (AWA) is an acquired reading disturbance associated with left posterior cerebral artery (PCA) infarction. Based on autopsy and neuroimaging, there are two explanations for its pathogenesis: a visual cortex-language cortex disconnection and a visual word-form agnosia. Our goal was to discover if more refined brain imaging in a case-control study would provide further imaging support for either of these hypotheses.
View Article and Find Full Text PDFActa Neurochir Suppl
November 2024
Instituto de Ciências da Saúde & Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia, Salvador, Brazil.
We report herein the case of a 41-year-old man operated on for a small inferior parietal lobule ganglioglioma with a sleep-awake-sleep protocol and language mapping to avoid major speech disorders. Postoperatively, however, writing disturbance was characterized by persistent graphemic errors that lasted for about 8 months. The topic is discussed in light of recent literature, exploring the possible relationship between writing difficulties and disconnections produced by a combination of resecting supramarginal gyrus components and interrupting arcuate fasciculus fibers.
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