Mohammed R. Daha is a successful and very productive scientist. He is internationally recognised for his expertise of Complement. In addition, he contributed to many other fields of Immunology, in particular Clinical Immunology within Internal Medicine. He did not only contribute to Nephrology and Transplantation, but also to Rheumatology, Infectious diseases and Pulmonology. He enjoyed teaching and he was also appreciated for his guidance of biomedical and clinical PhD's.
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Comparison of the efficacy of five different objective methods to evaluate the success of infraclavicular block; which one of them is a reliable and early indicator?
Ulus Travma Acil Cerrahi Derg
March 2023
Department of Anhestesiology and Reanimation, Harran University Faculty of Medicine, Şanlıurfa-Türkiye.
Background: Traditional methods that evaluate the success of peripheral nerve block have been replaced by methods that allow objective evaluations over time. Multiple objective techniques for peripheral nerve block have been discussed in the literature. This study aims to investigate whether perfusion index (PI), non-invasive tissue hemoglobin monitoring (SpHb), tissue oxygen saturation (StO2), tissue hemoglobin index (THI), and body temperature are reliable and objective methods to evaluate the adequacy of infracla-vicular blockage.
View Article and Find Full Text PDFRenal Endothelial Cytotoxicity Assay to Diagnose and Monitor Renal Transplant Recipients for Anti-Endothelial Antibodies.
Front Immunol
June 2022
Department of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Tissue-specific nonhuman leukocyte antigen (HLA) antigens can play crucial roles in allograft immunity and have been shown to trigger humoral responses leading to rejection of HLA-matched kidney allografts. Interest in the role of endothelial-specific antigens has grown over the past years, and several case reports have been described in which antibodies reacting with endothelial cells (ECs) are associated with rejection. Such antibodies escape the detection in conventional crossmatch tests as they do not react with lymphocytes.
View Article and Find Full Text PDFIn intra-articular distal humeral fractures: Can combined medial-lateral approach gain better outcomes than olecranon osteotomy?
Ulus Travma Acil Cerrahi Derg
July 2020
Department of Traumatic Orthopedics Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai-China.
Background: This research aimed to evaluate the functional outcomes of intra-articular distal humeral fractures treated through a combined medial-lateral approach and comparing with olecranon osteotomy simultaneously.
Methods: In this study, 62 distal humeral fractures patients were assessed retrospectively. The olecranon osteotomy was used in 30 cases (14 males, 16 females) and combined medial-lateral in 32 cases (15 males, 17 females).
Integrating Metabolomics, Genomics, and Disease Pathways in Age-Related Macular Degeneration: The EYE-RISK Consortium.
Ophthalmology
December 2020
Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:
Purpose: The current study aimed to identify metabolites associated with age-related macular degeneration (AMD) by performing the largest metabolome association analysis in AMD to date, as well as aiming to determine the effect of AMD-associated genetic variants on metabolite levels and investigate associations between the identified metabolites and activity of the complement system, one of the main AMD-associated disease pathways.
Design: Case-control association analysis of metabolomics data.
Participants: Five European cohorts consisting of 2267 AMD patients and 4266 control participants.
Association between loop diuretic dose changes and outcomes in chronic heart failure: observations from the ESC-EORP Heart Failure Long-Term Registry.
Eur J Heart Fail
August 2020
Unit of Cardiology, Department of Medicine, Karolinska Institutet, and Heart and Vascular Theme, Karolinska University Hospital, Stockholm, Sweden.
Aims: Guidelines recommend down-titration of loop diuretics (LD) once euvolaemia is achieved. In outpatients with heart failure (HF), we investigated LD dose changes in daily cardiology practice, agreement with guideline recommendations, predictors of successful LD down-titration and association between dose changes and outcomes.
Methods And Results: We included 8130 HF patients from the ESC-EORP Heart Failure Long-Term Registry.
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