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Practical naloxone communication tips for pharmacists: Lessons learned from the Linguistic Model of Patient Participation in Care.
Res Social Adm Pharm
January 2025
University of North Carolina at Chapel Hill, UNC Eshelman School of Pharmacy, 1 University Heights, CPO 2125, 114G Karpen Hall, Asheville, NC, 28804, USA. Electronic address:
Background: Opioid overdose is an ongoing public health issue in the rural United States and can be countered by increasing access to the opioid antagonist naloxone. Community pharmacists are well-positioned to offer and dispense naloxone to patients at risk of opioid overdose, but still experience a range of communication barriers. Understanding rural patient communication preferences is essential to prepare pharmacists to discuss naloxone in a patient-centered manner.
View Article and Find Full Text PDFA qualitative exploration of illness-related experiences, emotions, and coping among adults with postural orthostatic tachycardia syndrome (POTS).
J Health Psychol
January 2025
Vanderbilt University Medical Center, Nashville, TN, USA.
Postural orthostatic tachycardia syndrome (POTS) is a relatively common, burdensome condition of the autonomic nervous system characterized by orthostatic intolerance. This paper presents a subset of findings from a qualitative study investigating the lived experience and perspectives of adults with POTS. Twenty-nine individuals participated in a series of focus groups.
View Article and Find Full Text PDFKey Standards and Principles for Developing Evidence-Based Clinical Guidelines: Balancing Health Professional, Patient, Funder, and Government Needs.
Fertil Steril
January 2025
Monash Centre for Health Research and Implementation, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria, Australia; Department of Diabetes and Vascular Medicine, Monash Health, Victoria, Australia. Electronic address:
Clinical practice guidelines (CPGs) are critical tools to inform healthcare decision-making, yet development faces significant challenges in ensuring rigorous, reliable, and globally applicable recommendations. This review examines the essential standards and evolving approaches for creating high-quality, evidence-based guidelines that can effectively support clinical practice across diverse healthcare settings. Key standards for high-quality CPG development emerge from leading global health organizations, emphasizing several critical components - establishing a multidisciplinary development group, defining a clear and relevant scope, conducting systematic evidence reviews and meta-analyses, and ensuring transparency throughout the development process.
View Article and Find Full Text PDFDisease continuum centered on Parkinson's disease.
Eur Neuropsychopharmacol
January 2025
Beijing Institute of Basic Medical Sciences, 27 Taiping Road, Beijing 100850, China; Academy of Military Medical Sciences, 27 Taiping Road, Beijing 100850, China. Electronic address:
Parkinson's disease (PD), once viewed as a neurodegenerative disorder, is now increasingly recognized as part of a broader disease continuum, intricately linked to comorbidities across various organ systems. This study provides a snapshot of the disease continuum centered on PD, using a disease-wide association study (DWAS) involving 392,423 individuals-including 4,235 PD cases. This DWAS identifies disease clusters of PD comorbidities across the musculoskeletal, circulatory, digestive, and respiratory systems.
View Article and Find Full Text PDFPatient clusters based on demographics, clinical characteristics and cancer-related symptoms: A cross-sectional pilot study.
Eur J Oncol Nurs
January 2025
Clinical Research Service, IRCCS Policlinico San Donato, San Donato Milanese, Italy; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy. Electronic address:
Purpose: This study aimed to identify and preliminary validate distinct clusters of patients with cancer based on demographics, clinical characteristics, and symptoms and to inform future research on sample size requirements for achieving sufficient power in clustering analyses.
Methods: This cross-sectional pilot study involved 114 patients with cancer from two hospitals in northern Italy. Data were collected on demographics, clinical characteristics, and 20 symptoms using the Edmonton Symptom Assessment System in October 2022.
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