The synthesis of acyclic cucurbit[n]uril dendrimers G1-G3 that bear four dendrons on their aromatic sidewalls via thiolate S(N)2 chemistry is reported. G1-G3 are polycationic and can bind to pEGFP plasmid DNA as shown by dynamic light scattering (DLS), gel electrophoresis, and scanning electron microscopy (SEM). The gene delivery ability of G1-G3 is presented.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4670575 | PMC |
| http://dx.doi.org/10.1021/acs.orglett.5b03145 | DOI Listing |
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