α-Arylation/Heteroarylation of Chiral α-Aminomethyltrifluoroborates by Synergistic Iridium Photoredox/Nickel Cross-Coupling Catalysis.

Angew Chem Int Ed Engl

Department of Chemistry, University of Pennsylvania, Roy and Diana Vagelos Laboratories, 231 S. 34th St., Philadelphia, PA 19104-6323 (USA).

Published: January 2016

Direct access to complex, enantiopure benzylamine architectures using a synergistic iridium photoredox/nickel cross-coupling dual catalysis strategy has been developed. New C(sp(3))-C(sp(2)) bonds are forged starting from abundant and inexpensive natural amino acids.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795823PMC
http://dx.doi.org/10.1002/anie.201506147DOI Listing

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