The effect of aqueous solutions of dry ethanol extracts of Gratiola officinalis L., Helichrysum arenarium (L.) Moench, and anthocyanin forms of Zea mays L. on the dioxidin-induced lipid peroxidation in blood has been studied on rats. It is established that all these extracts are capable of reducing the amount of avera- ge-mass (AM) molecules and malonic dialdehyde (MDA) in rat blood plasma. The extract of Gratiola officinalis L. reduces the concentration of AM and MDA moleules by 43%. The extract of Helichrysum arenarium (L.) Moench reduces the concentration of AM molecules on the average by 18.66% (within 9.22 -34.81%) and MDA by 49.36% (within 34.12-79.75%). The Extract of anthocyanin forms of Zea mays L. does not reduce the concentration of AM mo- lecules, but reduces the amount of MDA in the blood of rats on average by 27.88% (within 21.58-37.82%) (p < 0.01).
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Anticancer Agents Med Chem
November 2024
Department of Pathological Anatomy, Saratov State Medical University n.a. V.I. Razumovsky, Saratov, Russia.
Introduction: Gratiola officinalis L. (hedge hyssop), a medicinal plant of the Scrophulariaceae family, has diuretic, purgative, and vermifuge properties. It is used as a herbal tea to treat chronic gastroenteritis, renal colic, jaundice, and intestinal worms.
View Article and Find Full Text PDFMaterials (Basel)
February 2023
Center for Collective Use of Experimental Oncology, Saratov State Medical University n.a. V.I. Razumovsky, Saratov 410012, Russia.
Flavonoid-containing extract has been studied in relation to breast carcinoma and human cervical cancer cells in encapsulated and native form. Encapsulation was realized in polymer shells, which were formed by the layer-by-layer method using sequential adsorption of poly(allylamine hydrochloride) and poly(sodium 4-styrenesulfonate) on the destructible cores. The extract was prepared by the author's method and characterized using high performance liquid chromatography.
View Article and Find Full Text PDFJ Ethnobiol Ethnomed
March 2020
Department of Functional Sciences I- Biochemistry, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
Background: Romanian ethnopediatrics has a long history of medicinal plant use. The main objective of the present review was to identify, collect, systematize, and prioritize the available bibliographical data related to medicinal plants traditionally used to treat various pediatric diseases in Romania during the 1860s-1970s.
Methods: Information was mainly obtained by manual systematic search in various relevant historical works focused on the traditional use of medicinal plants in Romania (1860s-1970s), found in the Archives of Romanian Academy Library and National Romanian Library.
Food Chem Toxicol
December 2019
Department of Food Science and Technology, Kaunas University of Technology, Kaunas, Lithuania. Electronic address:
Genotoxicity of B. officinalis, G. officinalis, V.
View Article and Find Full Text PDFArkh Patol
July 2019
V.I. Razumovsky Saratov State Medical University, Ministry of Health of Russia, Saratov, Russia.
Objective: To establish the mechanisms of pathomorphism of transplantable kidney cancer in rats that used flavonoid-containing hedge hyssop (Gratiola officinalis L.) extract in an in vivo experiments.
Material And Methods: The experiment was carried out on 30 male Wistar rats with transplantable kidney cancer PA.
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