A case of giant liposarcoma of the spermatic cord was reported. A 75-year-old man was admitted with a 25-year history of a slowly growing left scrotal solid mass without trans-illumination. The removed huge mass measuring 26.0 x 16.5 x 20.0 cm and weighing 4,500 g was confirmed to be a well-differentiated liposarcoma according to WHO classification. The patient died of acute pneumonia 5 months later, although the postoperative course was uneventful and he had no sign of recurrence.
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Liposarcoma of the spermatic cord (LSC) is extremely rare; < 200 cases were reported in the medical literature. Because of the rarity of these tumors and their presentation as a painless inguinal or scrotal mass, preoperative diagnosis is uncertain and they are frequently misdiagnosed as inguinal hernias.
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