Background: A surveillance tool was developed to assess dietary intake collected by surveys in relation to Eating Well with Canada's Food Guide (CFG). The tool classifies foods in the Canadian Nutrient File (CNF) according to how closely they reflect CFG. This paper describes the validation exercise conducted to ensure that CNF foods determined to be "in line with CFG" were appropriately classified.
Data And Methods: With statistical modelling, 8,000 simulated diets (500 for each of the 16 Dietary Reference Intake [DRI] age/sex groups) were generated using commonly consumed foods classified as "in line with CFG." Criteria for assessing the energy content and nutrient distributions of the simulated diets were based on factors considered in the development of CFG, including Estimated Energy Requirement (EER) and Dietary Reference Intake (DRI) values.
Results: The median energy content of the simulated diets was at or below reference EERs. Most age/sex group distributions had macronutrient profiles that met the assessment criterion of 80% of the distribution within the Acceptable Macronutrient Distribution Range, and almost all age/sex group distributions had a low prevalence (less than 10%) of micronutrient profiles below the Estimated Average Requirements. Overall, the findings indicate that diets consisting of foods that are commonly consumed by Canadians and that are "in line with CFG" have a low probability of energy excess and nutrient inadequacy.
Interpretation: The classification of foods in the CNF accurately reflects CFG recommendations and can be used to assess surveillance data.
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Eur J Clin Invest
December 2024
Department of Medicine, Masonic Cancer Center, University of Minnesota Medical Center, Minneapolis, Minnesota, USA.
Background: In addition to the long-known antibacterial actions of neutrophils, neutrophils are recognized to have a variety of other effects and are functionally diverse. Neutrophils can either stimulate or inhibit B cells and T cells, regulate NK development and activity, augment or direct the resolution of inflammation, act as myeloid-derived suppressor cells, modulate tumour growth and metastasis and trigger autoimmune diseases. CEACAMs 1, 3, 6 and 8 are expressed on human neutrophils.
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November 2024
Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares, Madrid, Spain (C.G.-S., A.G.-M., Á.S.-R., P.R.-P., L.S.-T., S.F.-S., C.F.-G., J.L.Z.).
Carbohydr Polym
January 2025
School of Life Sciences and Health Engineering, Jiangnan University, Wuxi 214122, China; Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, Jiangnan University, Wuxi 214122, China. Electronic address:
To address the main challenges for thoracoscopic lung cancer surgery, including persistent pulmonary air leaks and cancer recurrence, this study developed an in-situ adhesive that can effectively adhere to the lung and release the anticancer drug in response to pH. The adhesive was formulated using hydrophobically modified cold-water fish skin gelatin (hm-CFG) and cross-linking agent pullulan dialdehyde (PDA), in which succinic dihydrazide-modified doxorubicin (SDH-DOX) can be incorporated. Utilizing PDA could improve both cohesion and interfacial adhesion, while also offering drug-loading sites through the aldehyde groups that were not involved in cross-linking.
View Article and Find Full Text PDFAdv Pharmacol Pharm Sci
October 2024
Tea and Coffee Institute, Mae Fah Luang University, Chiang Rai 57100, Thailand.
Tea is a rich source of phytochemicals; their composition in tea extracts varies depending on the cultivar, climate, production region, and processing and handling processes. The method of extraction plays a crucial role in determining the biological effects of the bioactive compounds in tea leaves. However, reports on the catechin profiles and antioxidant activities of the extracts obtained from leaves at different stages of maturity are limited.
View Article and Find Full Text PDFCirc Heart Fail
November 2024
Instituto Ramón y Cajal de Investigación Sanitaria, Madrid, Spain (A.G.M., A.P.S., L.S.T., C.F.-G., J.L.Z.).
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