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Reporting Standards for Bayesian Network Modelling.
Entropy (Basel)
January 2025
Bayesian Intelligence, Upwey, VIC 3158, Australia.
Reproducibility is a key measure of the veracity of a modelling result or finding. In other research areas, notably in medicine, reproducibility is supported by mandating the inclusion of an agreed set of details into every research publication, facilitating systematic reviews, transparency and reproducibility. Governments and international organisations are increasingly turning to modelling approaches in the development and decision-making for policy and have begun asking questions about accountability in model-based decision making.
View Article and Find Full Text PDFPlant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals.
Bioengineering (Basel)
December 2024
Department of Cell & Systems Biology, University of Toronto, Toronto, ON M5S 3B2, Canada.
In spite of significant advancements in diagnosis and treatment, cancer remains one of the major threats to human health due to its ability to cause disease with high morbidity and mortality. A multifactorial and multitargeted approach is required towards intervention of the multitude of signaling pathways associated with carcinogenesis inclusive of angiogenesis and metastasis. In this context, plants provide an immense source of phytotherapeutics that show great promise as anticancer drugs.
View Article and Find Full Text PDFModeling of Jet Lag and Searching for an Optimal Light Treatment.
J Biol Rhythms
January 2025
Department of Physics and i3n, University of Aveiro, Aveiro, Portugal.
The role of the hierarchical organization of the suprachiasmatic nucleus (SCN) in its functioning, jet lag, and the light treatment of jet lag remains poorly understood. Using the core-shell model, we mimic collective behavior of the core and shell populations of the SCN oscillators in transient states after rapid traveling east and west. The existence of a special region of slow dynamical states of the SCN oscillators can explain phenomena such as the east-west asymmetry of jet lag, instances when entrainment to an advance is via delay shifts, and the dynamics of jet lag recovery time.
View Article and Find Full Text PDFEffect of modeling liquid application on color stability and surface roughness of single-shade composites.
BMC Oral Health
January 2025
Faculty of Dentistry, Department of Restorative Dentistry, Sivas Cumhuriyet University, Sivas, Turkey.
Objectives: The objective of this study was to examine the effects of modeling liquid application on the color stability and surface roughness of single-shade composites.
Materials And Methods: Single-shade composites were divided into 4 main groups according to their contents. A total of 64 disc-shaped samples (8 × 2 mm) were prepared, 16 in each group, by using Teflon molds.
D-Histidine modulated chiral metal-organic frameworks for discriminating 3,4-Dihydroxyphenylalanine enantiomers based on a chemiluminescence quenching mode.
Anal Chim Acta
February 2025
Key Laboratory of Luminescence Analysis and Molecular Sensing (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, China. Electronic address:
Background: Drug enantiomers often display distinguishable or even opposite pharmacological and toxicologic activities. Therefore it is of great necessity to discriminate enantiomers for guaranteeing safetyness and effectiveness of chiral drugs. Facile chiral discrimination has long been a noticeable challenge because of the minimal differences in physicochemical properties of enantiomers.
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