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| http://dx.doi.org/10.3201/eid2112.151232 | DOI Listing |
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Epidemiology, management and patient needs in myasthenia gravis: an Italian multistakeholder consensus based on Delphi methodology.
BMJ Open
December 2024
Neuroimmunology and Neuromuscular Diseases Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy
Objectives: To provide comprehensive information on the burden of myasthenia gravis (MG) in Italy, including the unmet needs of patients and several other aspects related to the disease, based on skilled viewpoints of MG experts.
Design: Iterative analysis conducted in accordance with the best practices of the Delphi method, including anonymity, controlled feedback, and statistical stability of consensus.
Setting And Participants: 24 clinicians, 18 public health experts and 4 patient associations experts completed all the Delphi iterations between 18 April and 3 July 2023, for a total of 46 participants from several Italian Regions.
Measurement and evaluation of low-carbon tourism development on islands: A case study in Changdao, China.
PLoS One
January 2025
Business School, Hanyang University, Seoul, Korea.
China's island tourism is still in the exploratory stage, and the carbon emissions due to island tourism development are still prominent. This study assesses the development of low-carbon tourism on Changdao Island in China. We constructed an evaluation model for low-carbon tourism on islands based on the driver-pressure-state-impact-response model, and the Entropy Weight Method-Analytical Hierarchy Process Method was combined with the weighting method to determine the index weights of ench evaluation-indicator.
View Article and Find Full Text PDFVolatile Profile of Bee Pollens: Optimization of Sampling Conditions for Aroma Analysis, Identification of Potential Floral Markers, and Establishment of the Flavor Wheel.
Food Sci Nutr
January 2025
Department of Postharvest, Supply Chain, Commerce and Sensory Science, Institute of Food Science and Technology Hungarian University of Agriculture and Life Sciences Budapest Hungary.
The volatile profile of bee pollen samples from Central and Eastern Europe was investigated by headspace solid phase microextraction (HS-SPME) combined with gas chromatography-mass spectrometry-olfactometry (GC-MS-O). Sampling conditions were optimized for the extraction of volatiles. Pollen odorants were extracted with six different fiber coatings, five various extraction times, three diverse extraction temperatures and three differing desorption times.
View Article and Find Full Text PDFAn accurate estimate of length of stay is necessary to derive passage population size for birds using a migration stopover site. In this study, we used VHF tags and a Motus automated telemetry array to estimate the length of stay of 385 Western Sandpipers () migrating through two stopover sites in British Columbia, Canada (Tofino and Fraser River Estuary) over the course of seven migration periods (three northward and four southward) from 2018 to 2021. The average length of stay of Western Sandpipers at the Tofino site on the west coast of Vancouver Island varied from 2 to 6 days and was shorter than the length of stay at the Fraser River Estuary, where the average length of stay varied from 4 to 8 days.
View Article and Find Full Text PDFBrief Report: Clinical Characteristics and Outcomes of Patients With Thoracic SMARCA4-Deficient Undifferentiated Tumors.
JTO Clin Res Rep
January 2025
Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Introduction: Thoracic SMARCA4-deficient undifferentiated tumors (SMARCA4-UTs) are a recently defined group of aggressive cancers in which the effectiveness of standard treatments for lung cancer is unknown.
Methods: We collected clinical, pathologic, and demographic variables from five institutions for patients whose tumors met criteria for SMARCA4-UTs (undifferentiated phenotype and loss of SMARCA4 (BRG1) by immunohistochemistry).
Results: We identified 92 patients with SMARCA4-UTs; 58 (63%) had stage IV disease at diagnosis and 16 (17%) developed recurrent or metastatic disease after initial diagnosis.
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