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Chromosomal Abnormalities in Embryonic and Somatic Stem Cells. | LitMetric

Chromosomal Abnormalities in Embryonic and Somatic Stem Cells.

Cytogenet Genome Res

Laboratorio di Biologia dello Sviluppo, Dipartimento di Biologia e Biotecnologie, Universitx00E0; degli Studi di Pavia, Pavia, Italy.

Published: June 2016

AI Article Synopsis

Article Abstract

The potential use of stem cells (SCs) for tissue engineering, regenerative medicine, disease modeling, toxicological studies, drug delivery, and as in vitro model for the study of basic developmental processes implies large-scale in vitro culture. Here, after a brief description of the main techniques used for karyotype analysis, we will give a detailed overview of the chromosome abnormalities described in pluripotent (embryonic and induced pluripotent SCs) and somatic SCs, and the possible causes of their origin during culture.

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Source
http://dx.doi.org/10.1159/000441645DOI Listing

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