Chamaecyparis obtusa essential oil (COE) has been widely used to treat allergic diseases and was suggested to exert anti-inflammatory, antioxidant, and antimicrobial effects. This study evaluated the effects of COE on pain-related behavior and pro-inflammatory cytokines in rats with carrageenan (CGN)-induced arthritis. Reduced dynamic weight load on inflamed joint in voluntarily walking rats was used as the behavior test for arthritic pain; 10% COE-treated group was significantly attenuated pain (6-8 h post-CGN injection) compared to VEH (mineral oil)-treated group. In addition, the protein levels of interleukin (IL)-1β, tumor necrosis factor-α, IL-6 (6-8 h), and cyclooxygenase (COX)-2 (8 h) within the synovial membrane, as well as IL-1β, COX-2 (6-8 h), and IL-6 (5-7 h) within the meniscus, of 10% COE-treated group were significantly reduced. The current results implicate that COE has anti-inflammatory and anti-nociceptive effects on arthritis in rats.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/09168451.2015.1075864 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A conifer metabolite corrects episodic ataxia type 1 by voltage sensor-mediated ligand activation of Kv1.1.
Proc Natl Acad Sci U S A
January 2025
Bioelectricity Laboratory, Department of Physiology and Biophysics, School of Medicine, University of California, Irvine, CA 92697.
Loss-of-function sequence variants in , which encodes the voltage-gated potassium channel Kv1.1, cause Episodic Ataxia Type 1 (EA1) and epilepsy. Due to a paucity of drugs that directly rescue mutant Kv1.
View Article and Find Full Text PDFCloning and functional characterization of volatile-terpene synthase genes from Chamaecyparis obtusa var. formosana.
Plant Sci
January 2025
School of Forestry and Resource Conservation, National Taiwan University, Taipei, Taiwan. Electronic address:
Chamaecyparis obtusa var. formosana is significant as a precious and endemic plant in Taiwan. The trunk, renowned for its excellent texture and color, is ideal for construction materials and furniture.
View Article and Find Full Text PDFUnexpectedly strong heat stress induction of monoterpene, methylbutenol, and other volatile emissions for conifers in the cypress family (Cupressaceae).
Sci Total Environ
December 2024
Department of Earth System Science, University of California, Irvine, CA, USA. Electronic address:
We investigated the biogenic volatile organic compound (BVOC) emission rates and composition of Cupressaceae species and how the emissions change in response to moderate warming and more severe heat stress. A total of 8 species from 7 distinct Cupressaceae genera were targeted in this study and exposed to laboratory-simulated heatwaves. Each plant was enclosed in a temperature-controlled glass chamber and allowed to equilibrate at 30 °C for 24 h.
View Article and Find Full Text PDFTranscriptomic and Phenotypical Analysis of the Physiological Plasticity of Roots under Different Nutrient Environments and Adjacent Plant Competition.
Plants (Basel)
September 2024
College of Forestry, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
seedlings undergo significant changes during growth due to different nutrient environments and adjacent plant competition, which is evident in the physiological plasticity changes in their roots. Therefore, in this experiment, 20 one-year-old elite family seedlings were selected as the test objects, and the different nutrient environments and adjacent plant competition environments in nature were artificially simulated. Four nutrient environments (N heterogeneous nutrient environment, P heterogeneous nutrient environment, K heterogeneous nutrient environment, and homogeneous environment) and three planting patterns (single plant, conspecific neighbor, and heterospecific neighbor) were set up to determine the differences in root physiological indexes and plasticity of different family seedlings, and the families and treatment combinations with higher comprehensive evaluation were selected.
View Article and Find Full Text PDFCell Extracts Derived from Cypress and Cedar Show Antiviral Activity against Enveloped Viruses.
Microorganisms
September 2024
Department of Health Science, School of Allied Health Sciences, Kitasato University, 1-15-1, Kitasato, Sagamihara 252-0373, Japan.
The antiviral efficacy of cell-extracts (CEs) derived from cypress ( (Siebold & Zucc.) Endl., ) and cedar ( (Thunb.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!