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Evolving Role of Exosomes in Plastic and Reconstructive Surgery and Dermatology.
Plast Reconstr Surg Glob Open
August 2024
Department of Dermatology, Mayo Clinic, Rochester, Minn.
Exosomes, or extracellular vesicles, represent the latest cell-free addition to the regenerative medicine toolkit. In vitro preclinical studies have demonstrated the safety and efficacy of exosomes, which vary based on source and biomanufacturing, for a myriad of potential therapeutic applications relevant to skin and soft tissue reconstruction. Primary search was performed in September 2021 on the MEDLINE database via PubMed and Ovid, with focus on articles about therapeutic application of exosomes or extracellular vesicles.
View Article and Find Full Text PDFExploring the relationship between spiritual care and patient advocacy of nurses from generations X, Y and Z working in intensive care clinics: A cross-sectional study.
Intensive Crit Care Nurs
October 2024
Department of Nursing, Faculty of Health Science, Bartın University, Bartın, Turkey.
Objective: To determine the relationship between spiritual care and patient advocacy across three generations of nurses working in intensive care units.
Design: Cross-sectional survey.
Methods: Data collection took place from July to August 2022 with 120 nurses in Turkey.
Background: Public involvement is important to the relevance and impact of health and care research, as well as supporting the democratisation of research. In 2020, the National Institute for Health Research (NIHR) reorganized and eliminated INVOLVE, an internationally recognised group that had played a central role in public involvement in the UK since 1996. Its remit was subsumed within a new center tasked with public involvement, participant recruitment, and evidence dissemination.
View Article and Find Full Text PDFAssessing the Knowledge and Awareness Among Selected Tertiary Students in the Accra Metropolis on Zoonotic Infections.
Environ Health Insights
November 2023
College of Health Yamfo, Sunyani, Ghana.
Background: Zoonotic infections are a serious threat to human health and a direct risk that could potentially be fatal. Animals both domestic and wild serve as reservoirs for zoonotic infections. Thus, frequent contact with animals might occasionally result in the transfer of infections from animals to people.
View Article and Find Full Text PDFMembrane contact site detection (MCS-DETECT) reveals dual control of rough mitochondria-ER contacts.
J Cell Biol
January 2024
Department of Cellular and Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, Canada.
Identification and morphological analysis of mitochondria-ER contacts (MERCs) by fluorescent microscopy is limited by subpixel resolution interorganelle distances. Here, the membrane contact site (MCS) detection algorithm, MCS-DETECT, reconstructs subpixel resolution MERCs from 3D super-resolution image volumes. MCS-DETECT shows that elongated ribosome-studded riboMERCs, present in HT-1080 but not COS-7 cells, are morphologically distinct from smaller smooth contacts and larger contacts induced by mitochondria-ER linker expression in COS-7 cells.
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