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| http://dx.doi.org/10.3389/fpls.2015.00897 | DOI Listing |
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Interlinking pathways: a narrative review on the role of IL-6 in cancer and atherosclerosis.
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Background And Objective: Interleukin-6 (IL-6) plays multifaceted roles in cancer and atherosclerosis. Initially recognized for its role in immune response and inflammation, IL-6 promotes tumor progression via the JAK-STAT and MAP kinase pathways and is associated with poor cancer prognoses. In atherosclerosis, IL-6 contributes to endothelial dysfunction and plaque formation.
View Article and Find Full Text PDFOverlooked and underpowered: a meta-research addressing sample size in radiomics prediction models for binary outcomes.
Eur Radiol
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Laboratory of Key Technology and Materials in Minimally Invasive Spine Surgery, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
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Peer reviewers' conflicts of interest in biomedical research: scoping review.
BMJ Evid Based Med
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Cochrane Denmark & Centre for Evidence-Based Medicine Odense (CEBMO), Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
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"Actor-critic" dichotomous hyperactivation and hypoconnectivity in obsessive-compulsive disorder.
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Coimbra Institute for Biomedical Imaging and Translational Research (CIBIT), University of Coimbra, 3000-548 Coimbra, Portugal; Institute for Nuclear Sciences Applied to Health (ICNAS), University of Coimbra, 3000-548 Coimbra, Portugal; Faculty of Medicine, Institute of Physiology, University of Coimbra, 3004-531 Coimbra, Portugal. Electronic address:
Dysfunctional response inhibition, mediated by the striatum and its connections, is thought to underly the clinical manifestations of obsessive-compulsive disorder (OCD). However, the exact neural mechanisms remain controversial. In this study, we undertook a novel approach by positing that a) inhibition is a dynamic construct inherently susceptible to numerous failures, which require error-processing, and b) the actor-critic framework of reinforcement learning can integrate neural patterns of inhibition and error-processing in OCD with their behavioural correlates.
View Article and Find Full Text PDFRecent Increase in Measles Cases Threatens Elimination Status in United States.
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Judy A. Beal is a Professor and Dean Emerita in the College of Natural, Behavioral, and Health Sciences at Simmons University, Boston, MA, and an MCN Editorial Board Member. Dr. Beal can be reached at
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