AI Article Synopsis
- The study presents a new multiplex real-time PCR-based assay for detecting high-risk HPV types in China, highlighting its effectiveness in identifying HPV 16 and 18.
- The assay is designed for both clinical settings and large-scale cervical screening, showcasing its sensitivity and reliability.
- This innovative and cost-effective approach aims to alleviate the economic burden of HPV detection in the country.
Article Abstract
In the present study, we describe the laboratory workflow and the clinical validation of a novel multiplex real-time PCR-based HPV assay in China. The cross-sectional validation analysis showed that this assay worked well for detection of 14 HR-HPV types and identification of HPV 16 and 18 in a single sensitive assay that is suitable for both clinical usage and high-throughput cervical screening purposes. We predict that this accurate, high-throughput and low-cost HPV assay can greatly reduce the heavy economic burden of HPV detection in China.
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| http://dx.doi.org/10.1007/s00705-015-2673-y | DOI Listing |
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