MIEC-SVM: automated pipeline for protein peptide/ligand interaction prediction.

Bioinformatics

Department of Chemistry and Biochemistry, UC, San Diego, La Jolla, CA 92093-0359 USA.

Published: March 2016

Motivation: MIEC-SVM is a structure-based method for predicting protein recognition specificity. Here, we present an automated MIEC-SVM pipeline providing an integrated and user-friendly workflow for construction and application of the MIEC-SVM models. This pipeline can handle standard amino acids and those with post-translational modifications (PTMs) or small molecules. Moreover, multi-threading and support to Sun Grid Engine (SGE) are implemented to significantly boost the computational efficiency.

Availability And Implementation: The program is available at http://wanglab.ucsd.edu/MIEC-SVM CONTACT: : wei-wang@ucsd.edu

Supplementary Information: Supplementary data available at Bioinformatics online.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907390PMC
http://dx.doi.org/10.1093/bioinformatics/btv666DOI Listing

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