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http://dx.doi.org/10.1164/rccm.201508-1561ED | DOI Listing |
BMC Nephrol
January 2025
Fresenius Medical Care Deutschland GmbH, Bad Homburg, Hessen, Germany.
Background: Results from the CONVINCE clinical trial suggest a 23% mortality risk reduction among patients receiving high-volume (> 23 L) hemodiafiltration. We assessed the real-world effectiveness of blood-based kidney replacement therapy (KRT) with hemodiafiltration vs. hemodialysis in a large, unselected patient population treated prior to and during the COVID-19 pandemic.
View Article and Find Full Text PDFActa Biochim Pol
December 2024
Department of Nephrology, Transplantology and Internal Diseases, Medical University of Gdansk, Gdańsk, Poland.
Various high-efficiency hemodialysis techniques exist, including different online high- volume hemodiafiltration (HDF) modes and expanded hemodialysis (HDx) utilizing dialyzers with medium cut-off (MCO) membranes. This study aimed to evaluate the efficacy of uremic toxin removal among four modalities: (I) HDx, (II) pre-dilution HDF (PRE-HDF), (III) mixed-dilution HDF (MIX-HDF), and (IV) post-dilution HDF (POST-HDF), each applied for 1 week in a randomized order. This research was a single-center, prospective, open-label, exploratory crossover study.
View Article and Find Full Text PDFInt J Artif Organs
December 2024
Global Systems Engineering, VS Machines, Care Enablement, Fresenius Medical Care Deutschland GmbH, Schweinfurt, Bavaria, Germany.
Clinical studies have shown that hemodiafiltration reduces morbidity and mortality of dialysis patients compared to hemodialysis alone. This is attributed to its superior middle molecule clearance compared to standard hemodialysis. However, doubts arose as to whether a high convective flux through the dialyzer membrane has an influence on the equilibrium concentration of small ions, especially that of sodium.
View Article and Find Full Text PDFKidney Int
November 2024
Division of Nephrology, Department of Medicine, University of California Davis Health, Sacramento, California, USA.
Persons with end-stage kidney disease treated with dialysis experience distressing reductions in quality of life and increased mortality. Few large, randomized trials in nephrology have reported on health-related quality of life. Rose et al.
View Article and Find Full Text PDFAnaesthesiologie
October 2024
Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Tübingen, Eberhard-Karls-Universität Tübingen, Hoppe-Seyler-Straße 3, 72076, Tübingen, Deutschland.
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