Surgical versus non-surgical management of abdominal injury.

Cochrane Database Syst Rev

Department of Community Health, University of Calabar Teaching Hospital, PMB 1278, Calabar, Nigeria.

Published: November 2015

Background: Injury to the abdomen can be blunt or penetrating. Abdominal injury can damage internal organs such as the liver, spleen, kidneys, intestine, and large blood vessels. There are controversies about the best approach to manage abdominal injuries.

Objectives: To assess the effects of surgical and non-surgical interventions in the management of abdominal trauma in a haemodynamically stable and non-peritonitic abdomen.

Search Methods: We searched the Cochrane Injuries Group's Specialised Register, The Cochrane Library, Ovid MEDLINE(R), Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations, Ovid MEDLINE(R) Daily and Ovid OLDMEDLINE(R), EMBASE Classic+EMBASE (Ovid), ISI WOS (SCI-EXPANDED, SSCI, CPCI-S & CPSI-SSH), CINAHL Plus (EBSCO), and clinical trials registers, and screened reference lists. We ran the most recent search on 17 September 2015.

Selection Criteria: Randomised controlled trials of surgical interventions and non-surgical interventions involving people with abdominal injury who were haemodynamically stable with no signs of peritonitis. The abdominal injury could be blunt or penetrating.

Data Collection And Analysis: Two review authors independently applied the selection criteria. Data were extracted by two authors using a standard data extraction form, and are reported narratively.

Main Results: Two studies are included, which involved a total of 114 people with penetrating abdominal injuries. Both studies are at moderate risk of bias because the randomisation methods are not fully described, and the original study protocols are no longer available. The studies were undertaken in Finland between 1992 and 2002, by the same two researchers.In one study, 51 people were randomised to surgery or an observation protocol. None of the participants in the study died. Seven people had complications: 5 (18.5%) in the surgical group and 2 (8.3%) in the observation group; the difference was not statistically significant (P = 0.42; Fischer's exact). Among the 27 people who had surgery, 6 (22.2%) surgeries were negative laparotomies, and 15 (55.6%) were non-therapeutic.In the other study, 63 people were randomised to diagnostic laparoscopy (surgery) or an observation protocol. There were no deaths and no unnecessary surgeries in either group. Four people did not receive the intervention they were assigned. There was no difference in therapeutic operations between the two groups: 3 of 28 in the diagnostic laparoscopy group versus 1 of 31 in the observation protocol group (P = 0.337).

Authors' Conclusions: Based on the findings of 2 studies involving a total of 114 people, there is no evidence to support the use of surgery over an observation protocol for people with penetrating abdominal trauma who have no signs of peritonitis and are stable.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11179156PMC
http://dx.doi.org/10.1002/14651858.CD007383.pub3DOI Listing

Publication Analysis

Top Keywords

abdominal injury
16
observation protocol
16
penetrating abdominal
12
ovid medliner
12
surgery observation
12
people
9
abdominal
8
management abdominal
8
non-surgical interventions
8
abdominal trauma
8

Similar Publications

Concurrent variations of left testicular vessels.

Anat Cell Biol

January 2025

Division of Anatomy, Department of Basic Medical Sciences, Manipal Academy of Higher Education, Manipal, India.

Knowledge of variations of the testicular vessels is essential for urologists, radiologists, and surgeons in general, as iatrogenic injuries of these vessels may affect the spermatogenesis severely. Though variations of testicular vessels are common, combined variations of these vessels are rare. We observed concurrent variations of left testicular vessels in an adult cadaver aged 70 years.

View Article and Find Full Text PDF

[The 510th case: fever of unknown origin, acute kidney injury].

Zhonghua Nei Ke Za Zhi

January 2025

Department of Infectious Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing100730, China.

A 65-year-old male was admitted to Peking Union Medical College Hospital. The patient had intermittent fever for 2 months with a maximum body temperature of 39.3 ℃ and elevated serum creatinine levels for 1 week.

View Article and Find Full Text PDF

Objective: To describe the presentation, outcomes, and management strategies for cases of subcapsular liver hematoma associated with preeclampsia, eclampsia, or HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome.

Methods: This was a case series of individuals with subcapsular liver hematoma managed at a single level IV center over a 10-year period, from 2013 to 2024. Presenting signs and symptoms, laboratory findings, time of onset, management strategies, acute perinatal and maternal outcomes, and long-term outcomes such as subsequent pregnancies were reviewed in the medical record and recorded.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA.

Background: Obesity in midlife, body mass index (BMI) of 30 kg/m or higher, is recognized as a contributor to Alzheimer disease (AD) later in life. Adiposity in visceral tissues such as liver is associated with increased systemic inflammation and impaired cognition. In this study, we aimed to investigate the relationship between MRI-derived Positron Density Fat Fraction (PDFF) and brain histology and neuroinflammation using Diffusion Basis Spectrum Imaging (DBSI) in cognitively normal midlife individuals.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA.

Obesity and abdominal adiposity in midlife are shown to increase the risk of Alzheimer disease. However, it is not clear whether midlife adiposity is associated with increased neuroinflammation. We aimed to investigate the associations of obesity, BMI of 30 kg/m or higher, and abdominal visceral and subcutaneous adipose tissue (VAT and SAT) with brain histology, using diffusion basis spectrum imaging (DBSI) analysis; METHOD: In total, 54 cognitively normal middle-aged subjects (50.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!