Salmonella Manipulates Autophagy to "Serve and Protect".

Cell Host Microbe

Department of Cell Biology, University of Virginia Health System, Charlottesville, VA 22908, USA; Department of Microbiology, University of Virginia Health System, Charlottesville, VA 22908, USA. Electronic address:

Published: November 2015

Many intracellular pathogens, including Salmonella typhimurium, trigger autophagy in host cells, which is widely thought to restrict intracellular growth and survival. In this issue of Cell Host & Microbe, Kreibich et al. (2015) demonstrate a role for the autophagic machinery in the repair of damaged Salmonella-containing vacuoles (SCVs).

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Source
http://dx.doi.org/10.1016/j.chom.2015.10.020DOI Listing

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