Adipose tissue autophagy status in obesity: Expression and flux--two faces of the picture.

Autophagy

a INSERM UMRS 1166, Sorbonne University, Pierre & Marie Curie, Institute of Cardiometabolism and Nutrition, Pitié-Salpetriere Hospital, Paris , France.

Published: December 2016

In the context of elevated prevalence of obesity-associated metabolic diseases in the human population worldwide, interest in the autophagy degradation pathway is increasing, due to close links with energy metabolism, nutritional state, and inflammation. Here we highlight recent data focusing on adipose tissue which demonstrate alterations in fat cell autophagic flux in human obesity.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835957PMC
http://dx.doi.org/10.1080/15548627.2015.1106667DOI Listing

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