Introduction: Puberty suppression by gonadotropin-releasing hormone analogs (GnRHa) is prescribed to relieve the distress associated with pubertal development in adolescents with gender dysphoria (GD) and thereby to provide space for further exploration. However, there are limited longitudinal studies on puberty suppression outcome in GD. Also, studies on the effects of psychological support on its own on GD adolescents' well-being have not been reported.
Aim: This study aimed to assess GD adolescents' global functioning after psychological support and puberty suppression.
Methods: Two hundred one GD adolescents were included in this study. In a longitudinal design we evaluated adolescents' global functioning every 6 months from the first visit.
Main Outcome Measures: All adolescents completed the Utrecht Gender Dysphoria Scale (UGDS), a self-report measure of GD-related discomfort. We used the Children's Global Assessment Scale (CGAS) to assess the psychosocial functioning of adolescents.
Results: At baseline, GD adolescents showed poor functioning with a CGAS mean score of 57.7 ± 12.3. GD adolescents' global functioning improved significantly after 6 months of psychological support (CGAS mean score: 60.7 ± 12.5; P < 0.001). Moreover, GD adolescents receiving also puberty suppression had significantly better psychosocial functioning after 12 months of GnRHa (67.4 ± 13.9) compared with when they had received only psychological support (60.9 ± 12.2, P = 0.001).
Conclusion: Psychological support and puberty suppression were both associated with an improved global psychosocial functioning in GD adolescents. Both these interventions may be considered effective in the clinical management of psychosocial functioning difficulties in GD adolescents.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/jsm.13034 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The citizen perspective on challenges and rehabilitation needs among individuals treated for head and neck cancer: a qualitative study.
Support Care Cancer
January 2025
Clinical Nursing Research Unit, Aalborg University Hospital & Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Purpose: In Denmark, the prevalence of head and neck cancer is approximately 17.000, and the incidence is increasing. The disease and treatment of this condition may lead to severe physical, psychological, and social consequences.
View Article and Find Full Text PDFRole of the gut microbiome in psychological symptoms associated with inflammatory bowel diseases.
Semin Immunopathol
January 2025
Department of Medicine II, Medical Faculty Mannheim, University Medical Center Mannheim, Heidelberg University, Mannheim, Germany.
The brain-gut axis constitutes the basis for the bidirectional communication between the central nervous system and the gastrointestinal tract driven by neural, hormonal, metabolic, immunological, and microbial signals. Alterations in the gut microbiome composition as observed in inflammatory bowel diseases can modulate brain function and emerging empirical evidence has indicated that interactions among the brain-gut microbiome-axis seem to play a significant role in the pathogenesis of both inflammatory bowel diseases and psychiatric disorders and their comorbidity. Yet, the immunological and molecular mechanisms underlying the co-occurrence of inflammatory bowel diseases and psychological symptoms are still poorly understood.
View Article and Find Full Text PDFEffectiveness of Poverty Reduction Programs on Psychological Development of Children and Adolescents at Risk of Poverty: A Systematic Review and Meta-analysis.
J Youth Adolesc
January 2025
Department of Social Work, the Chinese University of Hong Kong, Hong Kong, China.
Considering the potential detrimental impact of poverty on psychological development and the resulting harmful cycles, implementing poverty alleviation interventions is necessary for children and adolescents. Although several meta-analyses have demonstrated the effectiveness of monetary poverty reduction programs, there remains a significant gap in understanding how multidimensional poverty reduction strategies boost psychological development. This meta-analysis aims to address this gap by disclosing the impact of multifaceted anti-poverty interventions on the psychological development of children and adolescents.
View Article and Find Full Text PDF"To Whom Should I Refer Her?" Factors Contributing to Religious Informal Helpers' Referral Decisions for Women with Mental Illness and At-Risk Women: The Case of Israeli Balaniyot.
J Relig Health
January 2025
School of Social Work, Hadassah Academic College, Jerusalem, Israel.
Religious informal helpers may play a crucial role in recognizing and providing referrals to mental health professional for at-risk individuals, including those with mental illness, especially since members of religious communities tend to conceal their difficulties and to view religious leaders as a sole source of assistance. This quantitative study aimed to explore Jewish bathhouse attendants ("balaniyot") who assist women in their monthly immersion, a unique situation in which mental health symptoms (e.g.
View Article and Find Full Text PDFMusculoskeletal symptoms associated with aromatase inhibitors in the treatment of early breast cancer: A scoping review of risk factors and outcomes.
Support Care Cancer
January 2025
Fudan University School of Nursing, Shanghai, China and Fudan University Centre for Evidence-Based Nursing: A Joanna Briggs Institute Centre of Excellence, 305 Fenglin Rd, Shanghai, 200032, China.
Purpose: Aromatase inhibitor-associated musculoskeletal symptoms (AIMSS) are the most common adverse effects experienced by breast cancer patients. This scoping review aimed to systematically synthesize the predictors/risk factors and outcomes of AIMSS in patients with early-stage breast cancer.
Methods: A systematic search was conducted in PubMed, Web of Science, EMBASE, CINAHL, and the China National Knowledge Internet (CNKI) from inception to December 2024 following the scoping review framework proposed by Arksey and O'Malley (2005).
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!