Silver nanoparticles (nAg) are widely used in consumer products and the risk associated with their potential release into freshwater ecosystems needs to be addressed using environmentally realistic exposure concentrations. Here, the effects of low concentrations (0.5-5 μg L(-1)) of two different sized nAg (10 and 60 nm) and a silver nitrate positive control were evaluated in Gammarus roeseli following exposure for 72 h. Cellular, individual and functional endpoints were independently studied and the most striking results were reported for functional endpoints. Indeed, without a change in their feeding activity, the gammarids produced significantly fewer fine particles of organic matter when exposed to nAg, even at 0.5 μg L(-1) of 10 nm nAg. These functional endpoints seem to be efficient markers for detecting the early effects of nAg on G. roeseli.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.envpol.2015.10.036 | DOI Listing |
JACC Cardiovasc Interv
January 2025
Clinic for General and Interventional Cardiology/Angiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany. Electronic address:
Background: As transcatheter aortic valve replacement is performed increasingly in younger, low-risk patients, the need for commissural alignment and coronary access has increased. Design elements of the JenaValve Trilogy (JVT) transcatheter heart valve (THV) ensure both.
Objectives: This study sought to evaluate the outcome of patients with aortic stenosis (AS) treated with this novel transfemoral, self-expanding THV.
Urology
January 2025
Sapporo Medical University School of Medicine, Sapporo, Japan. Electronic address:
Objective: To prospectively assess the impact of transurethral resection of the prostate (TURP) on detrusor function using pressure flow study (PFS) at 5 years after surgery in a single center prospective non-randomized observational study.
Methods: Sixty consecutive male patients were prospectively enrolled and underwent TURP from November 2014 to November 2018. A questionnaire survey, free uroflowmetry and PFS were performed at baseline, and 6, 24 and 60 months after surgery.
Can J Cardiol
January 2025
Department of Cardiology, Istituto Auxologico Italiano, IRCCS, Milan, Italy; Department of Medicine and Surgery, University of Milano- Bicocca, Milan, Italy.
Background: In patients with moderate and severe secondary tricuspid regurgitation (STR), the effective regurgitant orifice area (EROA), corrected using the proximal isovelocity surface area (PISA) method for tricuspid valve leaflet tethering and low TR jet velocities, has an unclear threshold for identifying high-risk patients. This study aimed to establish a risk-based EROA cutoff and assess the impact of right ventricular (RV) remodeling on outcomes in low-risk STR patients according to EROA.
Methods: We included 513 consecutive outpatients (age 75±13 years, 47% male) with moderate and severe STR.
Circ J
January 2025
Department of Echo-imaging Center, Aizawa Hospital.
Background: Selexipag, an oral prostacyclin (PGI) receptor agonist, is approved for adult patients with pulmonary arterial hypertension (PAH). This study evaluated the efficacy and safety of selexipag for Japanese pediatric patients with PAH.
Methods And Results: The study enrolled 6 patients who received selexipag twice daily at an individualized dose based on body weight; maintenance doses were determined for each patient by 12 weeks after starting administration.
Eur Heart J Cardiovasc Imaging
January 2025
Department of Clinical Science and Education, Division of Cardiology, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.
Aims: The REDUCE-AMI trial showed that beta-blockers in patients with preserved left ventricular ejection fraction (LVEF) after acute myocardial infarction (AMI) had no effect on mortality or cardiovascular outcomes. The aim of this substudy was to evaluate whether global longitudinal strain (GLS) is a better prognostic marker than LVEF, and if beta-blockers have a beneficial effect in patients with decreased GLS.
Methods And Results: REDUCE-AMI was a registry-based randomized clinical trial.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!