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Chronic Leg Ulcerations and Subcutaneous Panniculitis due to Dermal Herpes Zoster in an Immunosuppressed Woman.
J Cutan Pathol
December 2024
Joan C. Edwards School of Medicine, Marshall University, Huntington, West Virginia, USA.
Herpes zoster (HZ) is a cutaneous viral disease that typically presents with a dermatomal vesicular eruption. Immunosuppressed patients are more likely to have atypical HZ involving chronic ulceration and disseminated distribution, making diagnosis a challenge. The current report describes a unique case of HZ in a woman with systemic lupus on immunosuppressive therapy manifesting as persistent lower extremity ulceration with diffuse dermal and endothelial infection and secondary panniculitis without epidermal involvement.
View Article and Find Full Text PDFRegressing Eruptive Disseminated Spitz Nevi: A Case Report.
Cureus
October 2024
Dermatology, The Third People's Hospital of Hangzhou, Hangzhou, CHN.
Article Synopsis
- Eruptive disseminated Spitz nevi (EDSNs) are rare skin growths that typically do not become cancerous and most often maintain their appearance, leading to psychological stress for those affected.
- An 18-year-old male experienced a sudden increase in pigmented nevi over a period of 20 days.
- After a two-year observation period, most of these nevi disappeared on their own without any medical intervention.
Erythroderma in the elderly.
J Dermatol
November 2024
Department of Dermatology, Fukushima Medical University, Fukushima, Japan.
Erythroderma is the end-stage condition caused by various inflammatory diseases, presenting with widespread generalized coalesced erythema on the trunk and extremities. Erythroderma is not a disease itself, but rather is a symptom expressing erythrodermic condition, which is frequently associated with inguinal lymphadenopathy, chills, and mild fever. The clinical characteristics include sparing the folds of the trunk and extremities (deck-chair sign), and cobblestone-like disseminated grouping prurigo; however, the deck-chair sign is not specific to papulo-erythroderma (Ofuji disease).
View Article and Find Full Text PDFStrategies for Diagnosing and Treating Disseminated Methicillin-Sensitive Staphylococcus aureus Infections: Insights From a Pustular Eruption.
Cureus
August 2024
Dermatology, Texas Tech University Health Sciences Center, Lubbock, USA.
Article Synopsis
- A 63-year-old man with a renal transplant and lymphoma undergoing chemotherapy (R-CHOP) developed fever and a widespread pustular rash, which were linked to septicemia.
- After ruling out other conditions, tests confirmed a methicillin-sensitive Staphylococcus aureus (MSSA) infection, primarily from his infected venous access port.
- Treatment involved removing the port and using a combination of antibiotics, leading to improvement, highlighting the significance of proper diagnosis and management of similar infections in immunocompromised patients.
Dermatological Manifestations of Disseminated Bacillus Calmette-Guerin Infection in the Intensive Care Unit.
Cureus
August 2024
Critical Care Medicine, Cliniques Universitaires Saint-Luc, Brussels, BEL.
Article Synopsis
- A 70-year-old patient with a history of bladder cancer treated with BCG developed symptoms like fever, fatigue, and a painful back lesion initially thought to be herpes zoster.
- Despite antiviral treatment and antibiotics, his condition worsened, leading to further imaging and biopsies that revealed non-caseating granulomas and confirmed disseminated BCG-itis.
- Treatment with a combination of antibiotics and corticosteroids ultimately resolved the skin lesions and improved the patient's health, highlighting the need for careful diagnosis in similar cases.
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