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[Intracytoplasmic sperm injection does not improve the clinical outcomes of the males with 100% teratozoospermia]. | LitMetric

AI Article Synopsis

  • The study aimed to assess whether intracytoplasmic sperm injection (ICSI) can enhance the success rates for male patients with 100% teratozoospermia during in vitro fertilization (IVF) processes.
  • A comparison of data from 152 couples revealed that while ICSI resulted in a higher percentage of transferrable embryos, IVF had better rates of normal fertilization and implantation; however, none of these differences were statistically significant for clinical outcomes.
  • The conclusion drawn was that ICSI does not improve the clinical outcomes for male patients diagnosed with 100% teratozoospermia.

Article Abstract

Objective: To investigate whether intracytoplasmic sperm injection (ICSI) can improve the clinical outcomes of the male patients with 100% teratozoospermia.

Methods: We retrospectively analyzed the clinical data of 152 couples undergoing in vitro fertilization-embryo transfer (IVF-ET), including 75 cycles of IVF and 77 cycles of ICSI. We compared the rates of normal fertilization, high-quality embryos, transferrable embryos, implantation, clinical pregnancy, and abortion between the two groups.

Results: In the 100% teratozoospermia patients the number of transferrable embryos was significantly lower in the IVF than in the ICSI group (78.91% vs 84.92%, P < 0.05), while the rates of normal fertilization and implantation were higher in the former than in the latter (60.26% vs 57.87% and 48.00% vs 39.55%, both P > 0.05). There were no statistically significant differences between the two groups in the female age, Gn days, Gn dose, BMI, infertility duration, endometrial thickness, and basal serum FSH and E2.

Conclusion: ICSI cannot improve the clinical outcomes of the male patients with 100% teratozoospermia.

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