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Collision tumours: our recent experience.
Postepy Dermatol Alergol
December 2024
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland.
Introduction: Collision skin lesions (CSL) are rare clinical and pathological entities, posing significant diagnostic and therapeutic challenges. These lesions comprise at least two distinct cell populations - benign and/or malignant neoplasms - that are adjacent yet clearly demarcated. CSL were categorized as collision tumours into three types: two benign lesions, one benign and one malignant lesion, and two malignant lesions, with the most common being basal cell carcinoma (BCC) and melanocytic naevus.
View Article and Find Full Text PDFEven though Leydig cell tumor (LCT) represents the most common neoplasia among testicular sex cord-stromal tumors (SCSTs), it is a rare condition, comprising 1-2% of all testicular tumors, with a 10% risk of malignancy most commonly located in retroperitoneal lymph nodes. LCTs may demonstrate various clinical manifestations - from asymptomatic intratesticular swelling through nonspecific symptoms such as loss of libido, impotence or infertility, up to feminizing or virilizing syndromes due to hormonal activity of the tumor. This article presents a case of Leydig cell tumor that was associated with azoospermia what have rarely been reported worldwide.
View Article and Find Full Text PDFImproved Image Quality Through Deep Learning Acceleration of Gradient-Echo Acquisitions in Uterine MRI: First Application with the Female Pelvis.
Acad Radiol
January 2025
Department of Radiology, Kantonsspital Baden, affiliated Hospital for Research and Teaching of the Faculty of Medicine of the University of Zurich, Im Ergel 1, 5404 Baden, Switzerland (D.H., A.M., R.R., J.H., R.A.K.-H.).
Rationale And Objectives: The aim of this study was to compare the image quality of a deep learning (DL)-accelerated volumetric interpolated breath-hold examination (VIBE) sequence with a standard (ST) VIBE sequence in assessing the uterus.
Materials And Methods: Between April and December 2023, a total of 61 female patients (aged 41 ± 14 years) who were referred for an magnetic resonance imaging (MRI) of the pelvis were included in this prospective study, after providing informed consent. All examinations were performed with a 1.
Probing Autism and ADHD subtypes using cortical signatures of the T1w/T2w-ratio and morphometry.
Neuroimage Clin
January 2025
The Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ontario, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, Canada; Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.
Autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) are neurodevelopmental conditions that share genetic etiology and frequently co-occur. Given this comorbidity and well-established clinical heterogeneity, identifying individuals with similar brain signatures may be valuable for predicting clinical outcomes and tailoring treatment strategies. Cortical myelination is a prominent developmental process, and its disruption is a candidate mechanism for both disorders.
View Article and Find Full Text PDFRecent advances on brain drug delivery via nanoparticles: alternative future materials for neuroscience applications; a review.
Rev Neurosci
January 2025
Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Science, Kerman, Iran.
Essentially, the blood-brain barrier (BBB) serves as a line of demarcation between neural tissues and the bloodstream. A unique and protective characteristic of the blood-brain barrier is its ability to maintain cerebral homeostasis by regulating the flux of molecules and ions. The inability to uphold proper functioning in any of these constituents leads to the disruption of this specialized multicellular arrangement, consequently fostering neuroinflammation and neurodegeneration.
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