A simple procedure for examining the seroconversion rates to measles vaccines in outlying communities is described; this involves the storage and transportation of dried-blood samples on filter paper, which is followed by the detection of measles-specific antibodies by means of a commercially-available immunofluorescence assay. Among 82 susceptible central Australian Aboriginal infants who were vaccinated at nine months of age, 76 (93% [95% confidence limits, 84.9%-96.6%]) children demonstrated seroconversion as a result of the vaccine, which is a figure that is similar to those that have been reported from some developing countries. The implications for a measles-vaccination policy are discussed.
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| http://dx.doi.org/10.5694/j.1326-5377.1989.tb136423.x | DOI Listing |
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