Patients with ischemic-type cerebral dyshematopoiesis have disturbances of blood cell function (their enhanced aggregation and reduction of leucocyte and erythrocyte deformation). Calcium antagonist nifedipine can neutralize these disturbances but it reduces blood cell sensitivity to it. The effectiveness of nifedipine can be increased by giving it in combination with prostacyclin. Blood cell sensitivity to this combination of agents changes insignificantly. It is recommended that nifedipine and medicinal agents which increase blood prostacyclin concentration be used in combination.
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