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Corrigendum to "Implementation of an ultra-sensitive microwell-based electrochemical sensor for the detection of Alzheimer's disease" [Biosens. Bioelectron. (2024) 247 115898].
Biosens Bioelectron
March 2025
Brain Science Institute, Biomedical Engineering, Korea Institute of Science and Technology, KIST School, Seoul, 02792, Republic of Korea; Department of Biomedical Engineering, University of Science and Technology, Daejeon, Republic of Korea.
Brain health PRO/Santé cerveau PRO: The development of a web-based program for dementia literacy and risk factor reduction.
J Prev Alzheimers Dis
March 2025
Department of Neurosciences, University of California, San Diego, California, USA; Alzheimer's Disease Cooperative Study, School of Medicine, University of California. San Diego California USA.
Background: Online educational programs focused on ways to improve brain health could increase participant literacy, empowerment, and engagement in activities that support personal brain health, potentially reducing dementia risk.
Objectives: Our goal was to develop an evidence-based online educational program with a focus on risk and protective factors for dementia. Here we present the rationale and features of the program and include results from a pilot study that assessed usability and acceptability.
Going beyond ATP binding site as a novel inhibitor design strategy for tau protein kinases in the treatment of alzheimer's disease: A review.
Int J Biol Macromol
March 2025
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Kasr El Aini Street, Cairo 11562, Egypt.
Alzheimer's disease (AD) is among the top mortality causing diseases worldwide. The presence of extracellular β-amyloidosis, as well as intraneuronal neurofibrillary aggregates of the abnormally hyperphosphorylated tau protein are two major characteristics of AD. Targeting protein kinases that are involved in the disease pathways has been a common approach in the fight against AD.
View Article and Find Full Text PDFStandardized Low-Resolution Brain Electromagnetic Tomography Does Not Improve EEG Alzheimer's Disease Assessment.
Neuroimage
March 2025
Medical University of Vienna, Institute of Artificial Intelligence, Vienna, Austria.
Quantitative EEG has been shown to reflect neurodegenerative processes in Alzheimer's disease (AD) and may provide non-invasive and widely available biomarkers to enhance the objectivization of disease assessment. To address EEG's major drawback-its low spatial resolution-many studies have employed 3D source localization. However, none have investigated whether this complex mapping into 3D space actually adds value over standard surface derivation.
View Article and Find Full Text PDFThe neuroprotective role of Humanin in Alzheimer's disease: The molecular effects.
Eur J Pharmacol
March 2025
Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt. Electronic address:
Humanin (HN) is an endogenous micropeptide also known as a mitochondria-derived peptide. It has a neuroprotective effect against Alzheimer's disease (AD) and other neurodegenerative diseases by improving hippocampal acetylcholine and attenuating the development of oxidative stress and associated neurotoxicity. HN protects the neuron from the toxic effects of amyloid beta (Aβ).
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