Chromatin-remodeling and the initiation of transcription.

Q Rev Biophys

Department of Structural Biology, Stanford University School of Medicine,Stanford,CA 94305,USA.

Published: November 2015

The nucleosome serves as a general gene repressor by the occlusion of regulatory and promoter DNA sequences. Repression is relieved by the SWI/SNF-RSC family of chromatin-remodeling complexes. Research reviewed here has revealed the essential features of the remodeling process.

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Source
http://dx.doi.org/10.1017/S0033583515000116DOI Listing

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