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A CONVEX COMPRESSIBILITY-INSPIRED UNSUPERVISED LOSS FUNCTION FOR PHYSICS-DRIVEN DEEP LEARNING RECONSTRUCTION.
Proc IEEE Int Symp Biomed Imaging
May 2024
Electrical and Computer Engineering, University of Minnesota, Minneapolis, Minnesota, USA.
Physics-driven deep learning (PD-DL) methods have gained popularity for improved reconstruction of fast MRI scans. Though supervised learning has been used in early works, there has been a recent interest in unsupervised learning methods for training PD-DL. In this work, we take inspiration from statistical image processing and compressed sensing (CS), and propose a novel convex loss function as an alternative learning strategy.
View Article and Find Full Text PDFShifting tides: A survey analysis of urologists' evolving attitudes toward focal therapy for prostate cancer.
Indian J Urol
January 2025
Section of Urology, Department of Surgery, University of Chicago, Chicago, IL, USA.
Introduction: Focal therapy (FT) is emerging as an alternative to radical treatment for prostate cancer (CaP). The purpose of this study is to assess the current perceptions of FT amongst urologists.
Methods: A 22-item questionnaire was e-mailed to members of the American Urological Association.
Needs assessment and Acceptability of a Community First Aid Responder programme to increase Out-of-hospital capacity in Kinshasa, Democratic Republic of Congo: A qualitative study.
Afr J Emerg Med
March 2025
Division of Emergency Medicine, Department of Family, Community and Emergency Care, Faculty of Health Sciences, University of Cape Town, South Africa.
Objective: Despite efforts in recent years to expand the availability of prehospital care in low- and middle-income countries, its availability remains limited in many regions. The World Health Organization advocates the development of layperson first responder programmes as a supportive step in building functioning prehospital systems. This study aimed to identify the need for, and acceptability of, a community first responder programme to increase out-of-hospital capacity in Kinshasa, Democratic Republic of Congo.
View Article and Find Full Text PDFA free-radical initiator-based carrier-free smart nanobomb for targeted synergistic therapy of hypoxic breast cancer.
RSC Adv
January 2025
State Key Laboratory for New Textile Materials & Advanced Processing Technology, Wuhan Textile University Wuhan 430200 P. R. China
Thermodynamic therapy (TDT) is a promising alternative to photodynamic therapy (PDT) by absorbing heat through thermosensitive agents (TSAs) to generate oxygen-irrelevant highly toxic free radicals. Therefore, TDT can be a perfect partner for photothermal therapy (PTT) to achieve efficient synergistic treatment of anoxic tumors using a single laser, greatly simplifying the treatment process and overcoming hypoxia limitations. However, the issues of how to improve the stability and delivery efficiency of TSAs still need to be addressed urgently.
View Article and Find Full Text PDFTargeting RNA splicing modulation: new perspectives for anticancer strategy?
J Exp Clin Cancer Res
January 2025
Department of Pharmacology, School of Pharmacy, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning Province, 110122, P. R. China.
The excision of introns from pre-mRNA is a crucial process in the expression of the majority of genes. Alternative splicing allows a single gene to generate diverse mRNA and protein products. Aberrant RNA splicing is recognized as a molecular characteristic present in almost all types of tumors.
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