A comparative study on the localization of prostatic inhibin peptide was carried out by the immunoperoxidase technique in prostates of humans, bonnet and langur monkeys, marmosets, dogs, and rats. A positive reaction was observed in the prostatic epithelial cells of humans, in all three species of monkeys, and in the rat, while the dog prostate did not exhibit any reaction. These observations indicate a close immunological similarity among human, monkey, and rat prostatic inhibin peptides.
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Sci Rep
January 2024
Department of Clinical Sciences, Division of Reproduction, The Centre for Reproductive Biology in Uppsala, Swedish University of Agricultural Sciences, 750 07, Uppsala, Sweden.
Knowledge of factors associated with semen quality may help in investigations of the aetiology and pathophysiology. We investigated the correlation between biomarkers for testicular cell function (anti-müllerian hormone, AMH, Inhibin B, testosterone, free androgen-index (testosterone/sex-hormone binding globulin), insulin like peptide 3, INSL-3), alkaline phosphate (ALP), canine prostate-specific esterase (CPSE), and heterophilic antibodies with dog variables, semen quality, and fertility. Blood and semen were collected from 65 Bernese Mountain Dogs.
View Article and Find Full Text PDFJ Family Med Prim Care
July 2022
Department of Biochemistry, Government Medical College, Nagpur, Maharashtra, India.
Introduction: Prostate cancer incidence is rising rapidly worldwide, which includes Asian countries too. There are a lot of controversies regarding the link between endogenous testosterone levels and prostate disorders. This study was conducted to understand the value of serum testosterone in predicting the risk and occurrence of prostate carcinoma.
View Article and Find Full Text PDFUrol Clin North Am
November 2022
Vascular Biology Research Laboratory, Boston Children's Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:
Aside from nonmelanoma skin cancer, prostate cancer is the most common cancer among men in the United States, and benign prostatic hyperplasia is the most common benign tumor found in men. Until recently, its endocrine functions and possible influence on the hypothalamic-pituitary axis have been relatively understudied. This review summarizes the current understanding of the potential endocrine functions of prostate cancer and benign prostate tissue.
View Article and Find Full Text PDFCureus
June 2022
Department of General Surgery, Kawasaki Medical School General Medical Center, Okayama, JPN.
The clinical management of brain metastasis (BM) and adrenal metastasis (AM) of cancer of unknown primary (CUP) can be challenging. A 73-year-old man presented to the hospital with sudden-onset hemiplegia. His laboratory data were normal, except for elevated levels of carcinoembryonic antigen (CEA) (33.
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