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Goals as Motives: Implications for Theory, Methods, and Practice.
Integr Psychol Behav Sci
January 2025
Leading Indicator Systems & Motivation Metrics, One Franklin Street, Suite 2508, Boston, MA, 02110, USA.
The concept of human goals is central to the study of psychology (i.e., motivation, behavior, and well-being), sociology (i.
View Article and Find Full Text PDFRab21-Targeted Nano Drug Delivery System-Based FFPG for Efficient Paclitaxel Delivery to Inhibit Lung Cancer Progression.
Pharmaceutics
January 2025
Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, 24 Heping Road, Harbin 150040, China.
: (PG) has been widely researched as a conductant drug for the treatment of lung diseases by ancient and modern traditional Chinese medicine (TCM) practitioners. Inspired by the mechanism and our previous finding about fructans and fructooligosaccharides from (FFPG), we developed a nano drug delivery system (NDDS) targeting lung cancer. The aim was to improve the efficiency of the liposomal delivery of Paclitaxel (PTX) and enhance the anti-tumor efficacy.
View Article and Find Full Text PDFSelf-Applied Daylight Photodynamic Therapy: A Paradigm Shift?
Int J Mol Sci
January 2025
Dermatology Department, Hospital Universitario Ramon y Cajal, Carretera M-607 km 9.1, 28034 Madrid, Spain.
Photodynamic therapy (PDT) involves the topical application of a photosensitizer and its activation by visible light, leading to the generation of protoporphyrin IX (PpIX) and reactive oxygen species. Daylight photodynamic therapy (dPDT), a variant utilizing natural sunlight as the energy source, enhances procedural flexibility by eliminating the need for specialized equipment. dPDT has been effectively used in dermatology to treat various cutaneous disorders, including neoplastic and infectious diseases.
View Article and Find Full Text PDFThe Effects of CrossFit Practice on Physical Fitness and Overall Quality of Life.
Int J Environ Res Public Health
December 2024
Centre of Research, Education, Innovation and Intervention in Sport and Porto Biomechanics Laboratory, Faculty of Sport, University of Porto, 4200-450 Porto, Portugal.
We have examined the impact of CrossFit workout sessions on physical fitness, comparing the obtained outcomes with the recommendations of the American College of Sports Medicine. In addition, we provide suggestions to improve training monitoring, as well as practical applications for researchers, coaches and practitioners. CrossFit imposes high cardiorespiratory and metabolic demands, promoting improvements in circulatory capacity, oxidative metabolism and muscular endurance.
View Article and Find Full Text PDFOpen-access Measurement Uncertainty Calculator MUCalc and its application to the quantification of Etizolam in tablets using High-Performance Liquid Chromatography (HPLC).
Sci Justice
January 2025
Leverhulme Research Centre for Forensic Science, School of Science and Engineering, University of Dundee, Nethergate, Dundee DD2 1HD, Scotland, UK.
The assessment of measurement uncertainty of an analytic method is a requirement for forensic toxicologists and drug chemists. There are two main methods for estimating measurement uncertainty: the bottom-up and the top-down approaches. The bottom-up approach has been suggested in current practice guides including 'Guide to the Expression of Uncertainty in Measurement (GUM)' published by ISO, and a guide to 'Quantifying Uncertainty in Analytical Measurement' published by EURACHEM.
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