AI Article Synopsis
- There are limited tools for analyzing B-cell lineage trees from next-gen sequencing data.
- The authors introduce two new online utilities that enable automated large-scale analysis and produce publication-quality results.
- Unlike existing tools, these utilities are compatible with various phylogenetic inference methods and antibody germline libraries, making them applicable across different species.
Article Abstract
There are at present few tools available to assist with the determination and analysis of B-cell lineage trees from next-generation sequencing data. Here we present two utilities that support automated large-scale analysis and the creation of publication-quality results. The tools are available on the web and are also available for download so that they can be integrated into an automated pipeline. Critically, and in contrast to previously published tools, these utilities can be used with any suitable phylogenetic inference method and with any antibody germline library and hence are species-independent.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617424 | PMC |
| http://dx.doi.org/10.1155/2015/323506 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!