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Front Artif Intell
January 2025
Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Introduction: Generating physician letters is a time-consuming task in daily clinical practice.
Methods: This study investigates local fine-tuning of large language models (LLMs), specifically LLaMA models, for physician letter generation in a privacy-preserving manner within the field of radiation oncology.
Results: Our findings demonstrate that base LLaMA models, without fine-tuning, are inadequate for effectively generating physician letters.
Comput Methods Programs Biomed
January 2025
Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, 400714, China.
Background And Objective: Cloud-based Deep Learning as a Service (DLaaS) has transformed biomedicine by enabling healthcare systems to harness the power of deep learning for biomedical data analysis. However, privacy concerns emerge when sensitive user data must be transmitted to untrusted cloud servers. Existing privacy-preserving solutions are hindered by significant latency issues, stemming from the computational complexity of inner product operations in convolutional layers and the high communication costs of evaluating nonlinear activation functions.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Artificial Intelligence and Data Science, College of Computer Science and Engineering, University of Hail, Hail, Saudi Arabia.
In the present digital scenario, the explosion of Internet of Things (IoT) devices makes massive volumes of high-dimensional data, presenting significant data and privacy security challenges. As IoT networks enlarge, certifying sensitive data privacy while still employing data analytics authority is vital. In the period of big data, statistical learning has seen fast progressions in methodological practical and innovation applications.
View Article and Find Full Text PDFbioRxiv
January 2025
Else Kroener Fresenius Center for Digital Health, Technical University Dresden, Fetscherstraße 74, Dresden, 01307, Saxony, Germany.
Rapid technological advancements have made it possible to generate single-cell data at a large scale. Several laboratories around the world can now generate single-cell transcriptomic data from different tissues. Unsupervised clustering, followed by annotation of the cell type of the identified clusters, is a crucial step in single-cell analyses.
View Article and Find Full Text PDFObjective: Federated research networks, like Evolve to Next-Gen Accrual of patients to Clinical Trials (ENACT), aim to facilitate medical research by exchanging electronic health record (EHR) data. However, poor data quality can hinder this goal. While networks typically set guidelines and standards to address this problem, we developed an organically evolving, data-centric method using patient counts to identify data quality issues, applicable even to sites not yet in the network.
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