Pancreatology
Department of Surgery, Surgical Oncology and Science, Sapporo Medical University School of Medicine, Sapporo, Japan.
Published: September 2016
Background/objectives: This study examined main pancreatic ductal spread in invasive ductal adenocarcinoma (IDC) of the pancreas.
Methods: Data from IDC patients who underwent radical surgery from 1990 to 2013 in our hospital were examined retrospectively. Incidence of intraductal spread of pancreatic cancer (IS), distance from the tumor edge, direction of IS and clinicopathological factors associated with the presence of IS were retrospectively examined with data from IDC patients who underwent radical surgery.
Results: Among 260 IDC patients who underwent surgery, 184 eligible cases, IS was identified in 42 patients (22.8%) and mean length of IS was 18.7 ± 21.6 mm. Mean distances on the ampullary and distal sides of IS were 11.1 mm and 11.6 mm. IS was significantly more frequent in localized tumors (UICC T1-2 vs. 3-4, p = 0.007), with tumor diameter ≤2 cm (p = 0.034) and in cases with scarce microscopic perineural invasion (p = 0.047). Among patients who underwent pancreaticoduodenectomy and distal pancreatectomy, IS presence (11.6 vs. 21.8%), mean distance to the contralateral side (11.4 vs. 11.6 mm), and IS ≥ 2 cm (3.3 vs. 4.7%) showed no significant differences. Overall survival did not differ significantly between IS-positive and -negative patients in the full analysis set or propensity score-matched patients (42 matched pairs).
Conclusions: In setting resectional margins at 2 cm, a small proportion of cases (3.8%) showed positive surgical margins. Localized tumor (UICC: T1-2, or <2 cm in diameter) requires more care with surgical margins, warranting intraoperative frozen sections.
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http://dx.doi.org/10.1016/j.pan.2015.09.017 | DOI Listing |
Retina
January 2025
Kresge Eye Institute/Department of Ophthalmology, Visual and Anatomical Sciences, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Purpose: To assess the effectiveness of split-thickness amniotic membrane (SAM) grafts in achieving closure of refractory or large macular holes (MH).
Methods: This retrospective study reviewed data from patients who underwent surgical repair of MHs using SAM grafts between January 2019 and December 2023. Key parameters, including best-corrected visual acuity (BCVA) and MH size, were evaluated both preoperatively and postoperatively.
J Neurosurg Case Lessons
January 2025
Department of Neurosurgery, Kurashiki Central Hospital, Kurashiki, Japan.
Background: Eagle syndrome is characterized by an elongated styloid process causing mechanical stress on the internal carotid artery (ICA). The authors present the case of a patient who had cervical ICA dissection with a nonelongated styloid process.
Observations: A 43-year-old man presented with left hemiparesis and hemispatial neglect.
PLoS One
January 2025
Division of Nursing, School of Health Sciences, Shinshu University, Matsumoto city, Nagano, Japan.
Type D personality, characterized by negative affectivity and social inhibition, has been associated with both the psychophysiology of coronary artery disease (CAD) and depressive disorders. However, few reports have described the impact of coping strategies in these patients. This study aimed to analyze the characteristics of type D personality and the coping strategies adopted by patients with CAD and to explore the factors associated with depressive tendencies during follow-up.
View Article and Find Full Text PDFJ Am Acad Orthop Surg
January 2025
From the Israel Defense Forces, Medical Corps, Kiryat Ono (Shapira, and Epstein), the Faculty of Medicine, The Hebrew University, Jerusalem (Shapira), the Sheba Medical Center, Tel Hashomer, Ramat Gan (Shapira), the Israel National Center for Trauma and Emergency Medicine Research, Gertner Institute of Epidemiology and Health Policy Research, Sheba Medical Center, Ramat Gan (Goldman, Givon, and Katorza), the Arrow Program for Medical Research Education, Chaim Sheba Medical Center, Tel-Hashomer, Ramat Gan (Katorza), the Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv (Katorza, Dudkiewicz, and Prat), the Rehabilitation Division, Sheba Medical Center, Tel Hashomer, Ramat Gan (Dudkiewicz), the Critical Care Division, Rambam Health Care Campus, Haifa (Epstein), the Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa (Epstein), and the Department of Orthopaedic Surgery, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel (Prat).
Background: In modern conflicts, extremities are mainly affected, with limb amputations required for approximately 5% of severely injured combatants and 7% of those with serious limb injuries. Amputations are some of the most challenging injuries endured by survivors, significantly affecting the patients and the healthcare system. This study aims to describe the rates, characteristics, and risk factors of limb amputations in patients with serious extremity trauma during the 2023 conflict in Israel.
View Article and Find Full Text PDFActa Orthop
January 2025
Department of Orthopaedic Surgery, Health Møre and Romsdal HF, Kristiansund Hospital, Kristiansund; Department of Neuromedicine and Movement Science, NTNU, Trondheim, Norway.
Background And Purpose: The optimal approach to the hip joint in patients with displaced femoral neck fractures (dFNF) receiving a total hip arthroplasty (THA) remains controversial. We compared the direct lateral approach (DLA) with the direct anterior approach (DAA) primarily on Timed Up and Go (TUG), and secondarily on the Forgotten Joint Score (FJS), the Oxford Hip Score (OHS), EQ5D-5L, and the EQ5D-VAS.
Methods: Between 2018 and 2023, we conducted a randomized controlled trial including elderly patients with dFNFs treated with THA.
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