When researchers are interested in the effect of certain interventions on certain individuals, single-subject studies are often performed. In their most simple form, such single-subject studies require that a subject is measured on relevant criterion variables several times before an intervention and several times during or after the intervention. Scores from the two phases are then compared in order to investigate the intervention effect. Since observed scores typically consist of a mixture of true scores and random measurement error, simply looking at the difference in scores can be misleading. Hence, de Vries & Morey (2013) developed models and hypothesis tests for single-subject data, quantifying the evidence in data for the size and presence of an intervention effect. In this paper we give a non-technical overview of the models and hypothesis tests and show how they can be applied on real data using the BayesSingleSub R package, with the aid of an empirical data set.
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http://dx.doi.org/10.1016/j.beth.2014.09.013 | DOI Listing |
Front Public Health
December 2024
School of Sociology and Political Science, Anhui University, Hefei, Anhui, China.
Objective: To investigate the impact of freshmen's mental health on their short-and long-term academic performance, as well as to provide empirical evidence for improving university students' mental health intervention tactics and higher education quality.
Methods: A multiple regression model was used to analyze student data from 3 years of enrollment at M University in Fujian Province.
Results: Different mental health problems have a significant impact on academic performance, which varies by gender, enrollment year, and subject.
Palliat Med
December 2024
Palliative and Supportive Care, Mater Misericordiae Ltd., South Brisbane, QLD, Australia.
Background: Xerostomia is a common and difficult symptom experienced by patients with cancer. Pilocarpine is a cholinergic agent that stimulates salivation.
Aim: To assess the feasibility of conducting a N-of-1 trial to determine the efficacy of pilocarpine orally dissolving tablets in patients with xerostomia.
Background: The safety of dietary interventions is often unmonitored. Wearable technology can track elevations in resting heart rate (RHR), a marker of physiologic stress, which may provide safety information that is incremental to self-reported data.
Methods: A single subject was placed on an isocaloric diet for four weeks.
MethodsX
June 2024
Department of Physiotherapy, Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka 576104, India.
Objective: Head and trunk control is essential for enhancing engagement and participation by improving visual integration, respiration, oromotor skill, arm control, and self-care. Our study protocol aims to investigate the effect of novel Head And Trunk Control Rehabilitation (HATCoRe) device on promoting head and trunk control in children with Cerebral Palsy (CP).
Method: This single subject multiple baseline design trial will include six children with CP aged two to 10 years, exhibiting delayed head and trunk control, having Gross Motor Function Classification System level IV and V will be enrolled.
J Mach Learn Res
April 2024
Department of Biostatistics and Bioinformatics, Emory University, Atlanta, GA 30322, USA.
Bayesian non-parametric methods based on Dirichlet process mixtures have seen tremendous success in various domains and are appealing in being able to borrow information by clustering samples that share identical parameters. However, such methods can face hurdles in heterogeneous settings where objects are expected to cluster only along a subset of axes or where clusters of samples share only a subset of identical parameters. We overcome such limitations by developing a novel class of product of Dirichlet process location-scale mixtures that enables independent clustering at multiple scales, which results in varying levels of information sharing across samples.
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