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THE ROLE OF PLASMA COPEPTIN LEVEL IN DETERMINING THE SEVERITY AND MORTALITY OF SUBARACHNOID HEMORRHAGE.
Acta Clin Croat
December 2023
Department of Emergency Medicine, Faculty of Medicine, Erciyes University, Kayseri, Turkey.
The study aimed to investigate the role of plasma copeptin level in setting the diagnosis, severity and mortality of patients with subarachnoid hemorrhage (SAH) admitted to the emergency department. We included patients aged ≥18 years who were diagnosed with SAH. Blood samples were collected from patients at the time of admission to the emergency department for assessment of plasma copeptin levels.
View Article and Find Full Text PDFPriority effects, nutrition and milk glycan-metabolic potential drive subspecies dynamics in the infant gut microbiome.
PeerJ
January 2025
Department of Medical Microbiology and Infection Prevention, Amsterdam University Medical Centers, Amsterdam, Netherlands.
Background: The initial colonization of the infant gut is a complex process that defines the foundation for a healthy microbiome development. is one of the first colonizers of newborns' gut, playing a crucial role in the healthy development of both the host and its microbiome. However, exhibits significant genomic diversity, with subspecies ( subsp.
View Article and Find Full Text PDFMultifaceted Analysis of Lactobacillus plantarum DMR14 Reveals Promising Antidiabetic Properties Through In Vivo Assays and Molecular Simulations.
J Cell Mol Med
January 2025
Microbiology Laboratory, Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi, Bangladesh.
Due to the growing concern about diabetes worldwide, we investigated the antidiabetic potential of Lactobacillus plantarum DMR14, assessing its effects on the diabetic mice and identifying safe, bioactive compounds targeting DPP4 protein for drug development through various methods, including in vivo assays, GC-MS analysis and molecular docking simulations. The animal experiments showed that after 3 weeks of treatment, the blood sugar levels of mice given the bacteria were reduced by 35.03% compared to baseline.
View Article and Find Full Text PDFEndothelial injury is one of the risk factors for the progression of vascular calcification in patients receiving maintenance dialysis.
Ren Fail
December 2025
Department of Nephrology, Chengyang District People's Hospital, Qingdao, China.
Background: Vascular calcification is common and progressive in patients with chronic kidney disease. However, the risk factors associated with the progression of vascular calcification in patients receiving maintenance dialysis have not been fully elucidated. Here, we aimed to evaluate vascular calcification and identify the factors associated with its progression in patients receiving maintenance hemodialysis.
View Article and Find Full Text PDFIdentification of the Novel HLA-B*15:245:02Q Allele in a Chinese Individual.
HLA
January 2025
Department of Transfusion Research, Wuhan Blood Center, Wuhan, China.
HLA-B*15:245:02Q differs from HLA-B*15:01:01:01 by two nonsynonymous nucleotides exchanges in exon 3.
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