BMC Res Notes
Internal and Subintensive Medicine of Ospedali Riuniti, Ancona, Italy.
Published: October 2015
Background: Hypernetworks are based on topological simplicial complexes and generalize the concept of two-body relation to many-body relation. Furthermore, Hypernetworks provide a significant generalization of network theory, enabling the integration of relational structure, logic and analytic dynamics. A pulmonary embolism is a blockage of the main artery of the lung or one of its branches, frequently fatal.
Results: Our study uses data on 28 diagnostic features of 1427 people considered to be at risk of pulmonary embolism enrolled in the Department of Internal and Subintensive Medicine of an Italian National Hospital "Ospedali Riuniti di Ancona". Patients arrived in the department after a first screening executed by the emergency room. The resulting neural hypernetwork correctly recognized 94% of those developing pulmonary embolism. This is better than previous results obtained with other methods (statistical selection of features, partial least squares regression, topological data analysis in a metric space).
Conclusion: In this work we successfully derived a new integrative approach for the analysis of partial and incomplete datasets that is based on Q-analysis with machine learning. The new approach, called Neural Hypernetwork, has been applied to a case study of pulmonary embolism diagnosis. The novelty of this method is that it does not use clinical parameters extracted by imaging analysis.
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http://dx.doi.org/10.1186/s13104-015-1554-5 | DOI Listing |
J Trauma Acute Care Surg
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From the Department of Surgery, Westchester Medical Center, New York Medical College, Valhalla, NY.
Background: Extracorporeal membrane oxygenation (ECMO) has emerged as a critical intervention in the management of patients with trauma-induced cardiorespiratory failure. This study aims to compare outcomes in patients with severe thoracic injuries with and without venovenous extracorporeal membrane oxygenation (VV-ECMO).
Methods: We performed a retrospective cohort study on Trauma Quality Improvement Program (2017-2021) and included all patients with isolated blunt thoracic injuries with Abbreviated Injury Scale score of ≥4 who required intubation.
Curr Med Imaging
January 2025
Department of Radiology, Peking Union Medical College Hospital [PUMCH], Chinese Academy of Medical Sciences & Peking Union Medical College [CAMS & PUMC], China.
Aims To evaluate the utility of unenhanced spectral imaging, electron density (ED) and overlay electron density (OED) images for assessing pulmonary embolisms in patients with suspected or confirmed acute pulmonary embolism (APE). Background Multiple spectral images can be extrapolated from spectral detector CT (SDCT), ED and OED images. ED and OED images are highly sensitive to moisture-rich tissues.
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Anesthesiology, Intensive Care and Emergency Department, Centro Hospitalar Universitário de Santo António, Porto, PRT.
Acute pulmonary embolism (PE) is a significant cause of cardiac arrests, with subsequent high mortality worldwide. Early recognition of acute PE allows earlier diagnosis, stabilization, and risk stratification, which are crucial in deciding the most adequate treatment option. However, diagnosis is sometimes difficult due to nonspecific clinical presentation.
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General Medicine, Dartford and Gravesham NHS Trust, Dartford, GBR.
Glioblastoma multiforme (GBM) is a World Health Organisation (WHO) grade IV glioma originating from astrocytes. It is the most common malignant primary tumour of the brain and central nervous system (CNS) and is associated with fast progression and violent local spread, with a median overall survival of approximately 15 months after diagnosis. Due to its late and varied presentation, it is often diagnosed only after it has grown considerably.
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Department of Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.
Background: Catheter-directed treatment (CDT) is an innovative treatment for patients with elevated risk pulmonary embolism (PE) to resolve embolus and restore pulmonary perfusion.
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