Erythema dyschromicum perstans.

Int J Dermatol

Instituto de Biomedicina, Caracas, Venezuela.

Published: April 1989

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http://dx.doi.org/10.1111/j.1365-4362.1989.tb02453.xDOI Listing

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Few studies discuss the co-management of vitiligo and acquired hyperpigmentation disorders (AHD) such as melasma, erythema dyschromicum perstans, post-inflammatory hyperpigmentation, drug-induced hyperpigmentation, and lichen planus pigmentosus. This review discusses clinical studies examining co-management strategies and identifies current practice gaps. Dermatology Life Quality Index scores are higher in individuals with vitiligo or melasma.

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Article Synopsis
  • * A review of existing literature found a lack of systematic studies on how these conditions impact patients' quality of life (QOL), with only seven studies meeting criteria to highlight impairment in QOL due to ADMH.
  • * Overall, the studies suggest that ADMH significantly affects QOL, potentially more so than melasma and similar to or less than vitiligo, emphasizing the need for clinicians to consider the psychosocial aspects when managing patients with these conditions.
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Introduction: Cutaneous adverse reactions to epidermal growth factor receptor inhibitors (EGFRi) are some of the most common side effects that patients experience. However, cutaneous adverse reactions that cause dyspigmentation in patients have been rarely reported. Erythema dyschromicum perstans (EDP) is a rare pigmentary condition that causes ashy-grey hyperpigmented macules and patches, with a few cases reported from EGFRi in the literature.

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