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Pax3 induces target-specific reinnervation through axon collateral expression of PSA-NCAM.
Prog Neurobiol
January 2024
Sorbonne Université & CNRS, IBPS-B2A, Biological Adaptation and Ageing, Paris France. Electronic address:
Damaged or dysfunctional neural circuits can be replaced after a lesion by axon sprouting and collateral growth from undamaged neurons. Unfortunately, these new connections are often disorganized and rarely produce clinical improvement. Here we investigate how to promote post-lesion axonal collateral growth, while retaining correct cellular targeting.
View Article and Find Full Text PDFThe European guideline on management of major bleeding and coagulopathy following trauma: sixth edition.
Crit Care
March 2023
Institute of Anaesthesiology, University Hospital Zurich, Raemistrasse 100, CH-8091, Zurich, Switzerland.
Article Synopsis
- Severe trauma poses a significant public health challenge globally, with post-traumatic bleeding being a major cause of preventable death and organ failure if not managed promptly.
- The sixth edition of the European guidelines provides evidence-based recommendations for clinicians treating bleeding trauma patients, using a concise format focused on high-quality studies.
- The guidelines include 39 clinical practice recommendations organized by key decision points to improve outcomes, emphasizing the importance of systematic diagnostic and treatment approaches in reducing mortality from traumatic injuries.
Electrical coupling regulated by GABAergic nucleo-olivary afferent fibres facilitates cerebellar sensory-motor adaptation.
Neural Netw
November 2022
Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, F-75012 Paris, France. Electronic address:
The inferior olivary (IO) nucleus makes up the signal gateway for several organs to the cerebellar cortex. Located within the sensory-motor-cerebellum pathway, the IO axons, i.e.
View Article and Find Full Text PDFMeasurement of Longitudinal Chromatic Aberration in the Last Crystalline Lens Surface Using Hartmann Test and Purkinje Images.
Sensors (Basel)
March 2022
Laboratorio de Sistemas Complejos, Departamento de Ciencias Básicas, Universidad Autónoma Metropolitana, Unidad Azcapotzalco, Av. San Pablo 180, Ciudad de México 02200, Mexico.
Research has shown that longitudinal chromatic aberration (LCA) of the human eye is generated across all of the eye's optical surfaces. However, it may not be necessary to measure the LCA from the first surface of the cornea to the retina, as it is known that most of the changes that can modify the path of light occur from the first surface of the cornea to the last surface of the crystalline lens. This investigation presents the study of an objective technique that allows the measurement of longitudinal chromatic aberration (LCA) on the last crystalline lens surface by developing a pulse width wavefront system using a Hartmann test, Purkinje image, and Zernike polynomial.
View Article and Find Full Text PDFApoptotic investigation of brain tissue cells in dogs naturally infected by canine distemper virus.
Virol J
August 2021
School of Life Science and Basic Medicine, Xinxiang University, Xinxiang, 453003, Henan, China.
Background: Canine distemper caused by canine distemper virus that belongs to the Morbillivirus genus of the Paramyxoviridae family is still a global epidemic significant infectious disease, especially in pet dogs in China and serious harm to the development of the dog industry. It has been known that apoptosis caused by the canine distemper virus can show in culture cells, lymphoid tissues, and the cerebellum. However, its occurrence in brain tissue cells remains unclear.
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