In the past few years, several endemic outbreaks of measles have been recognised, not only in children but also in adults, with severe and, occasionally, even fatal complications, possibly due to delayed diagnosis of the disease in adult medicine and decreasing vaccination rates. Furthermore, the treatment consists of supportive measures only. We present a case of severe measles pneumonitis in a 42-year-old man, a travel returnee, proven by direct virus isolation with PCR from bronchoalveolar lavage fluid. CT findings and pulmonary function testing revealed features of obstructive bronchiolitis; the patient was successfully treated with corticosteroids. He fully recovered, and lung function measurement returned to normal values. We conclude that acute measles can present as obstructive bronchiolitis and may be successfully treated with corticosteroids.
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http://dx.doi.org/10.1136/bcr-2015-210826 | DOI Listing |
Front Public Health
January 2025
Gulf Center for Disease Control and Prevention (CDC), Riyadh, Saudi Arabia.
In January 2021, the Gulf Health Council (GHC), established the Gulf Centre for Disease Prevention and Control (Gulf CDC) in Riyadh, marking a pivotal step in harmonizing health strategies, enhancing knowledge generation, and promoting evidence-based approaches to both communicable (CD) and non-communicable diseases (NCD). The Gulf CDC's mission includes consolidating the region's health information systems, crucial for monitoring disease burden and shaping effective public health policies. An initial assessment of public health surveillance systems across the Gulf Cooperation Council (GCC) member states was conducted by the Gulf CDC.
View Article and Find Full Text PDFCurr Pharm Biotechnol
January 2025
Center for Vaccine Innovation, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
The SARS-CoV-2 pandemic has highlighted the need for society, as a whole, to be prepared against potential pandemics caused by a variety of different viral families of concern. Here, we describe a roadmap towards the identification and validation of conserved T cell epitope regions from Viral Families of Pandemic Potential (VFPP). For each viral family, we select a prototype virus, the sequence of which could be utilized in epitope identification screens.
View Article and Find Full Text PDFPharmacol Res
January 2025
Korean Convergence Medical Science Major, Korea National University of Science and Technology (UST), Daejeon 34113, South Korea; Herbal Medicine Resources Research Center, Korea Institute of Oriental Medicine (KIOM), 111 Geonjae-Ro, Naju-Si, South Korea. Electronic address:
Aspilia africana (Pers.) C. D.
View Article and Find Full Text PDFTrop Med Int Health
December 2024
Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Background: Acute febrile illness is a common reason for seeking healthcare in low- and middle-income countries. We describe the diagnostic utility of a TaqMan Array Card (TAC) real-time polymerase chain reaction (PCR) panel for pathogen detection in paediatric and adult inpatients admitted with febrile illness.
Methods: In this prospective cohort study, we screened medical admissions for a tympanic temperature ≥38.
Pan Afr Med J
December 2024
World Health Organization, Expanded Programme on Immunization, Maternal Child Health and Nutrition, Addis Ababa, Ethiopia.
Introduction: following the detection of vaccine-derived poliovirus in 2019 in Ethiopia, response activities have been conducted including strengthening disease surveillance activities.
Methods: trend analysis study design of acute flaccid paralysis and measles surveillance data for the years 2021 and 2022 for Southwest Ethiopia Region was used. The non-polio acute flaccid paralysis (AFP) rate and stool adequacy rates were used to assess the AFP surveillance.
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